期刊文献+

阿司匹林抗栓外的心血管保护作用机制 被引量:12

原文传递
导出
摘要 目前,阿司匹林已广泛用于心脑血管疾病的二级预防,尤其对于急性冠状动脉综合征和急性缺血性卒中的治疗则更被认为是不可或缺的有效预防血栓形成的重要措施。毫无疑问,二级预防主要针对临床上已有冠心病和缺血性卒中等心脑血管疾病患者.
作者 杨国君
出处 《中华内科杂志》 CAS CSCD 北大核心 2012年第6期420-421,共2页 Chinese Journal of Internal Medicine
  • 相关文献

参考文献15

  • 1Patrono C, Garcia Rodriguez LA, Landolfi R, et al. Low-dose aspirin for the prevention of atherothrombosis. N Engl J Med, 2005,353 : 2373-2383.
  • 2杨兆军,单忠艳,田浩明,翁建平,周智广,杨文英.中国四省市阿司匹林预防心血管疾病用药现状调查[J].中华糖尿病杂志,2011,3(1):22-26. 被引量:28
  • 3Bartolucci AA, Howard G. Meta-analysis of data from the six primary prevention trials of cardiovascular events using aspirin. Am J Cardiol,2006 ,98 :746-750.
  • 4Libby P, Ridker PM, Hansson GK, et al. Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol,2009 ,54 :2129-2138.
  • 5Chiang N, Serhan CN. Aspirin triggers formation of anti- inflammatory mediators: New mechanism for an old drug. Discov Med, 2004,4:470-475.
  • 6May AE, Seizer P, Gawaz M. Platelets: inflammatory firebugs of vascular walls. Arterioscler Thromb Vasc Biol,2008,28:s5-10.
  • 7Langer HF, Gawaz M. Platelet-vessel wall interactions in atherosclerotic disease. Thromb Haemost, 2008,99:480-486.
  • 8Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev, 2004, 84 : 1381-1478.
  • 9Oberle S, Polte T, Abate A, et al. Aspirin increases ferritin synthesis in endothelial cells: a novel antioxidant pathway. Circ Res, 1998,82 : 1016-1020.
  • 10Grosser N, Schroder H. Aspirin protects endothelial cells from oxidant damage via the nitric oxide-cGMP pathway. Arterioscler Thromb Vase Biol, 2003,23 : 1345-1351.

共引文献27

同被引文献92

  • 1胡大一,张鹤萍,孙艺红,姜立清.华法林与阿司匹林预防非瓣膜性心房颤动患者血栓栓塞的随机对照研究[J].中华心血管病杂志,2006,34(4):295-298. 被引量:162
  • 2周伯荣,罗冰,王融,刘子凡,关海涛,许治强.阿司匹林间歇疗法在脑卒中二级预防中的临床价值[J].卒中与神经疾病,2006,13(4):205-207. 被引量:12
  • 3李焰生.脑梗死二级预防应该使用阿司匹林[J].中华内科杂志,2007,46(8):625-627. 被引量:8
  • 4张青山,邹江,赵丹,等.新型抗血小板药氯吡格雷研究进展[J].四川医学,2010,21(17):692-693.
  • 5Khan Q,Mehta JL. Relevance of platelet-independent effects ofaspirin to its salutary effect in atherosclerosis-related evens.J Atheroscler Thromb,2005 ,12 : 185 -901.
  • 6Bousser MG,Amarenco P,Chamorro A, et al. Terutroban versusaspirin in patients with cerebral ischaemic events ( PERFORM) : arandomised, double-blind, parallel-group trial. Lancet, 2011 ,377:2013-2022.
  • 7Monobe H, Yamanari H, Nakamura K,et al. Effects of low-doseaspirin on endothelial function in hypertensive patients.Clin Cardiol,2001,24:705-709.
  • 8Magen E, Viskoper JR, Mishal J,et al. Effects of low-dose aspirinon blood pressure and endothelial function of treated hypertensivehypercholesterolaemic subjects. J Hum Hypertens, 2005 ,19 : 667-673.
  • 9Ridker PM, Cushman M, Stampfer MJ, et al. Inflammation,aspirin,and the risk of cardiovascular disease in apparentlyhealthy men. N Engl J Med, 1997 ,336 : 973-979.
  • 10Weber C,Erl W, Pietsch A, et al. Aspirin inhibits nuclear factor-kappa B mobilization and monocyte adhesion in stimulated humanendothelial cells. Circulation, 1995 ,91 : 1914-1917.

二级引证文献85

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部