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盐酸特拉唑嗪与PKRP联合治疗前列腺增生合并高血压的临床研究 被引量：3

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摘要 目的评价盐酸特拉唑嗪与经尿道前列腺等离子双极电切术(PKRP)联合治疗前列腺增生(BPH)合并高血压患者的有效性、安全性及依从性。方法研究对象为临床型BPH合并高血压患者,均接受PKRP术、睡前口服盐酸特拉唑嗪1～6mg,随访3个月。评价指标:国际前列腺症状评分(IPSS)、收缩压、舒张压、最大尿流率(Q max),同时对不良事件进行分析。结果 IPSS从基线的21.55±4.82降至4周末的15.44±3.66和3月末的12.96±3.11(P<0.01),Qmax从基线的(7.63±4.41)mL/s提高至4周末的(12.55±1.34)mL/s和3月末的(15.51±2.92)mL/s(P<0.01),收缩压从基线的(161.00±12.33)mmHg降至4周末的(148.79±7.27)mmHg和3月末的(132.29±6.13)mmHg(P<0.01),舒张压从基线的(102.28±4.99)mmHg降至4周末的(95.98±4.61)mmHg和3月末的(81.09±4.26)mmHg(P<0.01)。结论采用盐酸特拉唑嗪与PKRP联合治疗前列腺增生合并高血压,不仅能有效改善患者下尿路梗阻症状,提高生活质量,有效控制血压,同时可提高患者的安全性和依从性。
作者 郑鸣 曾铭强 陈金洋 李树人 汪家兴
机构地区 湘潭市第一人民医院泌尿外科
出处 《现代泌尿外科杂志》 CAS 2012年第3期303-305,共3页 Journal of Modern Urology
关键词 前列腺增生 高血压 盐酸特拉唑嗪 经尿道等离子双极电切术
分类号 R697.32 [医药卫生—泌尿科学]
  • 相关文献

参考文献11

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二级参考文献19

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现代泌尿外科杂志
2012年 第3期

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