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消化性溃疡患者Leptin水平与HP感染的相关性研究 被引量:4

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摘要 目的:通过测定消化性溃疡(peptic ulcer,PU)患者组织黏膜中瘦素的表达,探讨瘦素(Leptin)、PU与HP感染三者的相关性,为HP的诊断提供新思路。方法:采用免疫组化法测PU患者黏膜组织中Leptin的水平,快速尿素酶试验和14C呼气试验方法检测是否HP感染。结果:黏膜组织中leptin的水平DU组明显高于对照组CG(P<0.005),HP+阳性的PU的瘦素表达率高于HP-(P<0.05),二者呈正相关。结论:PU患者组织黏膜的瘦素表达明显增高,其中HP阳性组高于阴性组。leptin可能参与了消化性溃疡的发病过程。PU、leptin、HP具有相关性。
出处 《黑龙江医药科学》 2012年第2期74-75,共2页 Heilongjiang Medicine and Pharmacy
基金 佳木斯大学研究生创新科研项目 编号:jyscx2011-014
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