疱疹病毒感染与缺血性脑卒中的关系研究

Relationship between herpes virus infection and ischemic stroke

目的研究单纯性疱疹病毒(HSV)感染与缺血性脑卒中的相关性。方法 48例缺血性脑卒中患者编入研究组,另选取50例同期医院健康门诊体检者列入对照组,取两组研究对象血液进行抗体检测和结果判定,分别测量和记录两组HSV-1IgM和HSV-2IgM抗体滴度OD值,并进行比较。结果研究组HSV-1IgM抗体滴度OD值为0.30±0.09,对照组为0.29±1.03,两组比较,差异无统计学意义,研究组HSV-2IgM抗体滴度OD值为0.08±0.01,明显高于对照组的0.01±0.00,数据经统计学比较,差异有统计学意义(P<0.05)。结论 HSV-2组的感染与缺血性脑卒中有密切相关性。

OBJECTIVE To discuss the relationship between herpes virus infection and the ischemic stroke.METHODS A total of 48 patients with ischemic stroke were assigned to the study group and 50 healthy people in the same period were distributed into the control group.The antibody testing was performed for the blood of the two groups of subjects,the testing results were determined,and the antibody titer OD value of HSV-1 IgM and HSV-2 IgM were measured and recorded separately.RESULTS The antibody titer OD value of HSV-1 IgM was 0.30±0.09 of the study group and 0.29±1.03 of the control group,the difference was not statistically significant;the antibody titer OD value of HSV-2 IgM of the study group was 0.08±0.01,significantly higher than 0.01±0.00 of the control group,the difference was statistically significant（P〈0.05）.CONCLUSION HSV-2 infection is closely related to the ischemic stroke.