C-反应蛋白检测在小儿细菌性肺炎及支原体肺炎中的应用

Detection of C-reactive protein applied in diagnosis of children with bacterial pneumonia and mycoplasma pneumonia

目的对比分析C-反应蛋白检测在小儿细菌性肺炎和支原体肺炎的诊断价值。方法选取148例肺炎患儿及同期进行健康体检的150例健康小儿作为研究对象,对所有受试者进行C-反应蛋白、肺炎支原体、血常规检测,对148例肺炎患儿治疗前后进行C-反应蛋白水平检测,比较健康小儿、支原体肺炎患儿、细菌性肺炎患儿的C-反应蛋白水平,比较细菌性肺炎患儿与支原体肺炎患儿治疗前后的C-反应蛋白水平,比较C-反应蛋白对不同类型肺炎患儿的阳性检测率,综合评价C-反应蛋白在肺炎患儿诊断鉴别中的价值。结果健康患儿、肺炎支原体患儿、细菌性肺炎患儿的C-反应蛋白分别为(3.58±0.79)、(14.82±3.69)、(68.54±28.31)mg/L;组间比较,肺炎组患儿明显高于健康组患儿(P<0.05),而细菌性肺炎组患儿明显高于支原体肺炎组患儿(P<0.05);细菌性肺炎患儿C-反应蛋白的阳性率为93.3%、支原体肺炎患儿为45.6%,患儿经治疗后,C-反应蛋白均明显下降,上述指标组间比较及治疗前后比较,差异均有统计学意义(P<0.05)。结论 C-反应蛋白检测可作为鉴别细菌性肺炎和支原体肺炎的有效手段,有助于临床医师采取相应的治疗方法及早治疗患儿,以免耽误病情。

OBJECTIVE To compare and analyze the C-reactive protein detection for the diagnosis of the children with bacterial pneumonia and mycoplasma pneumonia.METHODS A total of 148 children with pneumonia and 150 healthy children were chosen as the research subjects.All subjects were taken with the C-reactive protein,Mycoplasma pneumoniae,and blood testing.The levels of C-reactive protein of 148 cases of pneumonia children were tested before and after the treatment.The C-reactive protein levels of the healthy children,the children with mycoplasma pneumonia,and the children with bacterial pneumonia were compared.The C-reactive protein levels of the children with bacterial pneumonia and the children with mycoplasma pneumonia were compared before and after the treatment,the positive detection rates of C-reactive protein for the children with various types of pneumonia were compared,the value of C-reactive protection in the diagnosis of pneumonia was evaluated comprehensively.RESULTS The C-reactive protein levels of the healthy children,the children with mycoplasma pneumonia,and the children with bacterial pneumonia were respectively as follows：（3.58±0.79）mg/L,（14.82±3.69）mg/L,and（68.54±28.31）mg/L;as compared with the levels of C-reactive protein,the level of the children with pneumonia was significantly higher than that of the healthy children（P〈0.05）,the level of the children with bacterial pneumonia group was significantly higher than that of the children with Mycoplasma pneumonia（P〈0.05）;the positive detection rate of C-reactive protein of the children with bacterial pneumonia was 93.3%,the children with mycoplasma 45.6%;the level of C-reactive protein was significantly decreased after the treatment,the differences were statistically significant（all P〈0.05）.CONCLUSION The detection of C-reactive protein may be used as an effective way to identify the bacterial pneumonia and mycoplasma pneumonia,which can also help the clinicians to take appropriate treatment in a timely manner.