穴位埋线治疗肥胖型多囊卵巢综合征临床疗效观察

Clinical Observation of Acupoint Catgut-embedding Therapy in Treating Obesity-type Polycystic Ovarian Syndrome

【目的】观察穴位埋线治疗肥胖型多囊卵巢综合征(PCOS)患者的临床疗效。【方法】14例肥胖型PCOS患者均采用穴位埋线治疗3个月,治疗前后检测患者的体质量指数(BMI),检测黄体生成素(LH)、睾酮(T)、空腹血糖、空腹胰岛素、餐后2 h血糖、餐后2 h胰岛素水平及计算胰岛素抵抗指数(HOMA-IR),对各观察指标分别进行治疗前后比较。【结果】(1)14例患者治疗前均有月经稀发或闭经表现,经过穴位埋线治疗后有8例恢复周期在45 d内自行月经来潮,超过45 d仍未来经者予口服孕酮使之撤药性出血。其中合并不孕者10例,有2例分别在治疗第3个月和第4个月时成功宫内妊娠。(2)体质量、血睾酮和LH水平、BMI、空腹胰岛素和餐后2 h胰岛素水平及HOMA-IR值治疗前后比较,差异均有统计学意义(P<0.05或P<0.01),空腹血糖、餐后2 h血糖治疗前后比较,差异无统计学意义(P>0.05)。【结论】穴位埋线可有效控制肥胖型PCOS患者的体质量,并能有效调节患者的内分泌激素水平,值得临床推广应用。

Objective To observe the therapeutic effect of acupoint catgut-embedding therapy in treating obesity-type polycystic ovary syndrome（PCOS）.Methods Fourteen obesity-type PCOS patients were treated with acupoint catgut-embedding therapy for 3 months.Body mass index（BMI） was examined,and the levels of luteinizing hormone（LH）,testosterone（T）,fasting blood glucose（FBG）,fasting insulin,postprandial blood sugar,and 2-hour postprandial insulin as well as insulin resistance index（HOMA-IR） were measured before and after treatment.The therapeutic effect was evaluated after comparison of the observation indexes.Results Before treatment,oligomenorrhea or amenorrhea occurred in all of the 14 patients.After treatment,menstrual onset occurred within 45 days in 8 patients,and oral use of progesterone was for the rest patients to induce withdrawal uterine bleeding.Ten PCOS patients were complicated with infertility,but 2 patients had intrauterine gestation successfully on the 3rd or 4th month of treatment.BMI,LH,T,fasting insulin,postprandial insulin and HOMA-IR were decreased after treatment and the differences were significant（P0.05 or P0.01 compared with those before treatment）,but the differences of fasting blood glucose and 2-hour postprandial blood sugar were insignificant（P0.05）.Conclusion Acuoint catgut-embedding therapy can effectively control the weight of obesisty-type PCOS patients,and can availably regulate the levels of endocrine hormones.