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氧化型低密度脂蛋白与动脉粥样硬化关系的研究 被引量：1

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摘要 动脉粥样硬化（AS）是大多数心脑血管疾病发生的病理基础。目前已得到公认的动脉粥样硬化的主要危险因素有性别、年龄、血脂异常、吸烟、糖尿病等，低密度脂蛋白（LDL）作为血浆中胆固醇的主要载体，在诸多因素中，是唯一不需要其他危险因素协同而诱发动脉粥样硬化的危险因素，是动脉粥样硬化发生过程中的重要环节之一。
作者 岳福仁
机构地区 天津医科大学宝坻临床学院
出处 《菏泽医学专科学校学报》 2012年第1期67-69,共3页 Journal of Heze Medical College
关键词 氧化低密度脂蛋白 动脉粥样硬化 内皮细胞
分类号 Q51 [生物学—生物化学] R543.5 [医药卫生—心血管疾病]
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参考文献17

  • 1Ehara S, Ueda M, Naruko F. et al. Elevated levels of OXidized low den sity lipoprotein show a positive 21ationship with the severity of acute coronary syndromes[J].Cireulation,2001, 103(15): 1955-1960.
  • 2Sigari F, Lee C,Witzum ,T L, et al. F ibrohlasts that ovcrexp ress 15- lipoOXygenase generate bioactive and minimally modified LDL [J] .Arterioscler Thromb Vaso Biol, 1997, 17: 3639-3643.
  • 3Harda SM, Kinoshita M, Kam ido H, etal Oxidized low density lip-oprotein induces apoptosis in cultured human umbilical vein endo-thelial cells by common and unique mechanisms[J].J B iol Chem,1998 273(16).968-9687.
  • 4陈玉成,梁玉佳,刘瑞,黄明慧,曾智.氧化低密度脂蛋白对血管内皮细胞骨架的损伤及其机制[J].心血管康复医学杂志,2004,13(4):320-321. 被引量：41
  • 5Vielama SA, Mironova M, Ku JR, et al. Oxidized LDI. further en-hances expression of adhesion molecules in Chlamydophila pneu-moniae-infeeted endothelial cells[J].J Lipid ReS 2004, 45( 5):873-880.
  • 6Bahaman SQ Lennon D.J Febbraio M, et al A CD36-dependent signaling cascade is necessary for m acrophage foam cell formation [J].Cell Metab,2006,4(3):211-221.
  • 7严鹏科,廖端芳,杨永宗.Caveolin-1表达对血管平滑肌细胞胆固醇逆转运的调节作用[J].中国动脉硬化杂志,2002,10(5):379-383. 被引量：34
  • 8Katslka H, Kume N, Nlyamoto S et al Oxidized LDL modulater Bax/Bcl-2 through the lectin like OX-LDI. receptorl in vascular smooth muscle cells[J]. Ateriascler 'Yhromb Vase Biol, 2001, 21 (6): 955-960.
  • 9MarikoFukumoto, TetsuoShoji, MasanoriEmoto, et al Antibodies against OXidized LDL and carotid artery intima-media thickness inahealthy population arterioscler[J]. Thromb Vasc Bid, 2000, 20: 703-707.
  • 10Santos AO,Fonseca FA, Fischer SM, et al High circulating auto antibodies against human OXidized low-density lipoprotein are relat ed to stable and lower titers to stable clinical situation[J].Clinica Chimica Acta,2009, 406(1-2):113-118.

二级参考文献24

  • 1董军,陈文祥,李健斋.高效液相色谱测定微量胆固醇氧化产物[J].生物化学与生物物理进展,1996,23(2):179-182. 被引量：9
  • 2Fraley A E, Tsimikas S. Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease [ J ]. Curt Opin Lipid ,2006,17 (5) :502-509.
  • 3Holvoet P, Vanhaecke J, Janssens S,et al. Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease [ J ]. Circulation, 1998,98 ( 15 ) : 1487-1494.
  • 4Anselmi M, Garbin U, Agostoni P, et al. Plasma levels of oxidized-low-density lipoproteins are higher in patients with unstable angina and correlated with angiographic coronary complex plaques [ J ]. Atherosclerosis,2006,185 ( 1 ) : 114-120.
  • 5O'Neill W. Issues in management of acute coronary syndromes: effects of bleeding[ J]. Clin Cardiol,2007,30( 10 Suppl 2) :II 1-3.
  • 6Wang J J,Zhang C N, Gong J B, et al. Development of new enzyme-linked immunosorbent assay for oxidized lipoprotein (a) by using purified human oxidized lipoprotein(a) autoantibodies as capture anti-body[ J ]. Clin Chim Acta,2007,385 ( 2 ) :73-78.
  • 7Tsimikas S, Brilakis E S, Miller E R, et al. Oxidized phospholipids, Lp (a) lipoprotein, and coronary artery disease[J]. N Engl J Med, 2005,353( 1 ) :46-57.
  • 8[1]Ross R. The pathogensis of atherosclerosia a perspective for the 1900s [J]. Nature, 1993, 362, 80.
  • 9[2]Lee JS, Gotlieb AI. Understanding the role of the cytoskeleton in the complex regulation of the endothelial repair [J]. Histology & Histopathology, 2003, 18 (3): 879-887.
  • 10[3]Kuhne W, Besselmann M, Noll T, et al. Disintegration of cytoskeletal structure of actin filaments in energy-depleted endothelial cellas [J]. Am J Physiol, 1993, 263 (2): H1599.

共引文献83

同被引文献9

  • 1Chadban S,Chan M,Fry K,et al.The CARI guidelines.Protein requirement in adult kidney transplant recipients [J].Nephrology (Carlton),2010,15 Suppl 1;S68-71.
  • 2Diao Y,Li H,Li H,et al.Association of serum levels of lipid and its novel constituents with the different stages of esophageal carcinoma[J].Lipids Health Dis,2009,8(1):48.
  • 3Li H,Diao YT,Li HQ,et al,The association between ser- um levels of:oxLDL-IgG and oxLDL-IgM autoantibody with adult acute myeloblastic leukaemia[J].Lipids Health Dis,2010,9(1):11.
  • 4Antonov AS,Munn DH,Kolodgie FD,et al,Aortic endo- thelial cells regulate proliferation of human monocytes in vitro via a mechanism synergistic with macrophage colo- ny-stimulating factor.Convergence at the cyclin E/p27(Kip1) regulatory checkpoint[J].J Clin Invest,1997,99(12):2867-2876.
  • 5Vassalotti JA,Stevens LA,Levey AS.Testing for chronic kidney disease:a position statement from the National Kidney Foundation[J].Am J Kidney Dis,2007,50(2):169-180.
  • 6Zahran A,El-Husseini A,Shoker A.Can cystatin C re- place creatinine to estimate glomerular filtration rate? A literature review[J].Am J Nephrol,2007,27(2):197-205.
  • 7Yang HQ,Qiu FQ,Jin K,et al.High plasma levels of oxi- datively modified low-density lipoproteins are associated with the suppressed expression of immunomodulatory molecules in patients with hematological malignancies[J].Exp Ther Med,2015,9(6).2394-2400.
  • 8刘从江,李芬,张磊,刘剑华.慢性肾病患者细胞因子测定的临床意义[J].放射免疫学杂志,2008,21(6):514-515. 被引量：2
  • 9范广忠,高文杰,郑雪峰,张希军,周桂芹.检测糖尿病肾病患者血清细胞因子的意义[J].中国实用医刊,2012,39(13):33-35. 被引量：5

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菏泽医学专科学校学报
2012年 第1期

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