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超声心动图评价年轻成人左室构型及其影响因素 被引量:4

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摘要 目的应用超声心动图观察年轻成人左室构型,并评价血压(BP)和肥胖等心血管疾病危险因素对其影响。方法应用M型超声心动图测量624例年轻成人(年龄23岁~39岁)收缩期和舒张期左室内径(LVDs和LVDd)及舒张期室间隔和左室后壁厚度(IVSd和LVPWd),计算左室壁相对厚度(LVRWT)和左室质量指数(LVMI),根据LVRWT>0.42,LVMI男性>50g/m2,女性>47g/m2将左室几何形态分为正常(normal geometry,NG)组、向心性重构(concentric remodeling,CR)组、离心性肥厚(eccentrichypertrophy,EH)组和向心性肥厚(concentric hypertrophy,CH)组,同时测量血压、空腹血糖和血脂等。应用多变量Logistic回归分析观察肥胖(BMI)和BP等心血管疾病危险因素与左室几何形态的相关性。结果 NG组、CR组、EH组和CH组的发生率分别为61.6%、12.0%、16.7%和10.2%。与NG组比较,EH组和CH组收缩压(SBP)、舒张压(DBP)、体质量指数(BMI)和空腹血糖(Glu)高于NG组,高密度脂蛋白(HDL-C)低于NG组,上述指标CR组与NG组及EH组与CH组间无统计学意义(P>0.05)。与CR组比较,EH组BMI和肥胖比例明显高于CR组(P<0.05),CH组的高血压比例高于CR组(P<0.05),EH组和CH组之间无统计学意义。多变量Logistic回归分析显示:SBP、DBP和BMI均与EH组和CH组相关(P<0.05),而与CR组无明显相关性。结论肥胖和高血压可改变年轻成人左室几何形态,对左室发生EH和CH有预测价值,提示早期防治年轻成人肥胖和高血压有重要意义。
出处 《中西医结合心脑血管病杂志》 2012年第5期528-529,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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