祛风清热法治疗感冒后咳嗽的疗效观察

Observation on the curative effect of Qufengqingre method in treatment of the patients with cough after cold

目的观察祛风清热法治疗感冒后咳嗽的疗效。方法选取感冒后咳嗽患者74例，随机分为对照组（36例）和观察组（38例）。对照组予罗红霉素150mg／次，2次／d；酮替芬1mg／次，每晚1次；枸橼酸喷托维林50mg／次，3次／d。观察组予祛风清热法为基础的汤剂，每剂水煎煮2次取汁混合约300ml，分早晚口服。两组疗程均为7～14d。观察两组的疗效、症状评分以及不良反应。结果对照组治愈7例，有效21例，无效8例；观察组治愈17例，有效18例，无效3例。观察组总有效率为92．1％，优于对照组的77．8％（χ2=4．16，P〈0．05）。两组治疗前咳嗽和痰量评分分别为（2．18±0．73）分和（1．09±0．27）分，（2．26±0．65）分和（1．12±0．23）分，治疗后分别为（1．11±0．37）分和（0．65±0．16）分，（0．72±0．19）分和（0．35±0．08）分。两组治疗前评分比较差异均无统计学意义（t=1．29，1．31，均P〉0．05）；两组治疗前后比较和两组问治疗后比较差异均有统计学意义（t=2．68，2．59，2．43，2．41，2．53，2．37，均P〈0．05）。两组均未见明显的不良反应。结论祛风清热法治疗感冒后咳嗽的疗效显著。

Objective To explore the curative effect of Qufengqingre method in treatment of the patients with cough after cold. Methods 74 patients with cough after cold were selected and randomly divided into the control group（36 cases） and the observation group （38 cases）. The control group was given roxithromycin （150 mg every time, two times every day）, ketotifen（ 1 mg every time, one time every night）, pentoxyverine citrate （50mg every time, 3 times every day）. The observation group was given Qufengqingre decoction, and the decoction was boiled in water twice per dose, and mixed juice about 300 ml was abtained for morning and evening oralling. The efficacy ,symptoms score and adverse reactions were observed. Results In the control group ,7 patients were cured, effective in 21 cases,invalid in 8 cases, and in the observation group, 17 cases were cured, effective in 18 cases,invalid in 3 cases. The total effective rate of the observation group was 92.1% higher than 77.8% of the control group （χ2 = 4. 16, P 〈 0.05 ）. The cough and sputum score of the two groups before treatment was （2.18 ± 0.73 ） points and （1.09 ± 0.27 ） points, （2. 26 ± 0.65 ） points and （ 1.12 ± 0.23 ） points, respectively, and after treatment was （ 1.11 ± 0.37 ） points and （0. 65 ±0.16） points, （0.72 ±0.19） points and（0.35 ±0.08） points. Differences in scores between the two groups before treatment were not statistically significant（ t = 1.29,1.31, all P 〉 0.05 ） ; In the two groups before and after treatment were statistically significant（ t = 2.68,2.59,2.43,2.41, all P 〈 0.05 ） ; After treatment the difference be- tween the two groups were statistically significant （ t = 2.53,2. 37, all P 〈 0.05 ）. Both groups had no obviously adverse reactions. Conclusion Qufengqingre method in treatment of the patients with cough after cold had remarkable effect.