支气管肺炎患儿C-反应蛋白检测的意义

Clinical sigrificance of C-reactive protein testing for mycoplasma pneumonia

目的探讨C-反应蛋白（CRP）检测在小儿支气管肺炎诊断与治疗中的作用和意义。方法对341例急性呼吸道感染患儿标本进行CRP定量检测，并以150例健康儿童作对照，比较CRP水平与CRP检测阳性率。结果根据诊断标准，341例患儿中细菌性肺炎128例（37．54％），CRP阳性率95．31％；支原体肺炎151例（44．28％），CRP阳性率31．13％；病毒性肺炎62例（18．18％），CRP阳性率6．45％。细菌性肺炎、支原体肺炎、病毒性肺炎与对照组CRP水平、CRP阳性率差异均有统计学意义（均P〈0．01）。结论d,JL支原体肺炎比病毒性肺炎CRP升高显著，因此CRP可作为鉴别和诊断支原体肺炎的重要辅助病原学检测指标。

Objective To explore the dinical significance of C-reactive protein （CRP） testing for diagnosis and treatment of children with bronchial pneumonia. Methods 341 samples of children with acute respiratory infections were detected with CRP quantitative analysis and CRP level and CRP positive rates were compared with 150 healthy children as control specimens. Results According to diagnostic criteria, 128 cases of bacterial pneumonia were found in 341 patients,accounting for 37.54% ,CRP positive rate was 95.31% ;151 cases of mycoplasma pneumonia,accounting for 44.28%, CRP positive rate was 31. 13 % ; and 62 cases of viral pneumonia, accounting for 18.18%, CRP positive rate was 6.45 %. CRP levels, CRP-positive rates of bacterial pneumonia, mycoplasma pneumo- nia, viral pneumonia compared with the control group were significantly different （ P 〈 0.01 ）. Conclusion CRP of mycoplasma pneumonia increased significantly than viral pneumonia, thus CRP could be used as an important second- ary pathogen detection indicators for identification and diagnosis of mycoplasma pneumonia.