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GnRHA方案与GnRHa长方案在IVT-ET治疗中的应用观察 被引量:1

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摘要 目的对比观察性腺激素释放激素(GnRH)拮抗剂方案(GnRHA)与GnRH激动剂(GnRHa)长方案在体外受精—胚胎移植(IVT-ET)治疗中的应用效果。方法将卵巢储备功能正常的不孕症患者261例随机分为两组,均接受IVF-ET治疗,A组131例采用GnRHA方案,B组130例采用GnRHa长方案。结果 A组促性腺激素(Gn)使用剂量、使用天数、卵巢过度刺激综合征发生率分别为(18±4.5)支、(9.0±1.4)d、0.8%,B组分别为(28±3.8)支、(12.5±1.2)d、5.6%,两组相比,P均<0.05。两组获卵数、受精率、卵裂率、可用胚胎形成率、移植胚胎数、临床妊娠率、流产率、多胎率比较,P均>0.05。结论对于卵巢储备功能正常的不孕症患者,IVT-ET治疗中应用GnRHA方案与GnRHa长方案效果相当,但GnRHA方案可减少Gn剂量,缩短治疗时间。
机构地区 中国人民解放军
出处 《山东医药》 CAS 2012年第18期82-83,共2页 Shandong Medical Journal
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二级参考文献28

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