杂环表面活性剂的合成及杀菌性能研究

Synthesis and Sterilization Property of Heterocyclic Surfactants

以吡啶与1-溴代烷(溴代辛烷、溴代癸烷、溴代十二烷和溴代十四烷)为原料,合成了一系列杂环表面活性剂。用正交试验确定合成目标产物的较佳工艺条件为:反应温度90℃,反应时间5h,溴代烷与吡啶的摩尔比1∶1。利用IR,1 H NMR对杂环表面活性剂进行结构表征。测定了目标产物对大肠杆菌、金黄色葡萄球菌和枯草芽孢杆菌的杀菌性能。结果表明:所合成的杂环表面活性剂对上述三种细菌具有良好的杀菌性能。

A series of heterocyclic surfactants were prepared with pyridine and 1-bromoalkanes（bromooctane,bromodecane,bromododecane or bromotetradecane）.The best reaction conditions for synthesis of the target products were optimized by orthogonal test program.The reaction temperature was 90℃,the reaction time was 5 h,and the mole ratio of bromoalkane and pyridine was 1∶1.The products were characterized by IR and 1H NMR.The target products＇ sterilization properties for colibacillus,staphylococcus aureus,bacillus subtilis were determined.The results showed that the heterocylic surfactants had excellent sterilization properties for the above three kinds of bacteria.