益气清瘟解毒颗粒剂治疗流行性感冒的临床疗效评价

Clinical Effect of Granules for Qi-Refreshing and Pestilence-Eliminating-Detoxifying in Treatment of Influenza

目的评价益气清瘟解毒颗粒剂治疗流行性感冒的有效性和安全性。方法将临床收集的123例表寒里热型流行性感冒患者随机分为中药治疗组与西药对照组,中药治疗组口服益气清瘟解毒颗粒剂,西药对照组服用抗病毒药治疗。结果益气清瘟解毒颗粒剂的退热效果优于西药对照组,中药治疗组改善流感患者的症状积分优于西药抗病毒药物,其疾病疗效、中医证候疗效及主要症状疗效均优于西药对照组,且具有抑制免疫炎性损伤的趋势。结论益气清瘟解毒颗粒剂治疗表寒里热型流行性感冒疗效显著,安全可靠。

Objective To estimate the effect and safety of Granules for Qi-Refreshing and Pestilence-Eliminating-Detoxifying（GQPD） in treatment of influenza. Methods Totally 123 influenza patients with the syndrome of Exterior-Cold and Interior-Heat in traditional Chinese medicine（TCM） were randomly divided as TCM group receiving QRPE and control group receiving antiviral drug. Results Compared with the antiviral drug,GQPD was better in antipyretic effect and improvement of influenza symptom scores,being better in effects for disease,TCM syndrome,and cardinal symptoms of influenza.And it showed a tendency to inhibit the immune-inflammatory injury. Conclusion The GQPD is effective and safe in treatment of influenza with TCM syndrome of Exterior-Cold and Interior-Heat.