阻塞性睡眠呼吸暂停低通气综合征患者认知功能与焦虑情绪相关研究

Correlation between Cognition and Anxiety in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

目的了解阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的认知功能与焦虑状况,探究两者之间的关系。方法对152例经多导睡眠仪(PSG)检查确诊的OSAHS患者采用蒙特利尔认知功能评估量表(MoCA)及焦虑自评量表(SAS)进行调查。结果患者MoCA总均分为(24.63±2.568)分,认知功能总分<26分者113例,占74.3%;SAS得分为(47.50±9.573)分,标准分>50分者64例,占42.1%。认知功能得分与SAS得分呈相关性(r=-0.343,P=0.000)。结论 OSAHS患者的认知功能普遍受损,且部分存在焦虑情绪。认知功能与焦虑情绪密切相关。

Objective To explore the correlation between cognition and anxiety in patients with obstructive sleep apnea hypopnea syndrome（OSAHS）. Methods A total of 152 patients with OSAHS confirmed by an all-night（7 h）polysomnogram（PSG） were evaluated by Montreal Cognitive Assessment（MoCA） and Zung self-rating anxiety scale（SAS）. Results The total mean score of MoCA for the patients with OSAHS was（24.63±2.568）.About 74.3%（113） of the patients obtained total score of of MoCA26.The average SAS score was（47.50±9.573）.About 42.1%（64） of the patients obtained SAS score50.There were close correlations between MoCA score and SAS score（r=-0.343,P=0.000）. Conclusion Most of the OSAHS patients exhibit cognitive impairment,and some of them have anxiety symptoms.The cognitive function and anxiety are closely correlated.