保乳术与改良根治术治疗乳腺癌的临床对比研究

Clinical Comparative Study of Breast-conserving Surgery and Modified Radical Mastectomy in the Treatment of Patients with Early-stage Breast Cancer

目的：比较早期乳腺癌患者保乳术与改良根治术的疗效。方法：2004年9月~2011年6月期间,我科共收治57例早期乳腺癌患者。根据手术方式将前述乳腺癌患者分成2组,观察组31例,接受保乳术;对照组26例,接受改良根治术。现比较两组患者的临床疗效。结果：①两组患者的手术时间、住院时间、术中出血量、术后并发症发生率、术后美容效果相比差异有统计学意义（P均〈0.05）。②经过3年时间的随访,两组患者的术后局部复发率、远处转移率等指标差异无统计学意义（P均〉0.05）。结论：保乳术与改良根治术治疗早期乳腺癌患者的疗效相同,但是保乳术具有手术时间、住院时间短,术中出血量少,术后并发症发生率低,术后美容效果好等优点,因此保乳术是早期乳腺癌患者首选的手术方式。

Objective：To compare the therapeutic effect of breast-conserving surgery and modified radical mastectomy in the treatment of patients with early-stage breast cancer.Methods：From September 2004 to June 2011,57 patients with early-stage breast cancer were admitted into our department.According to their surgical treatment way,these before-mentioned patients were divided into 2 groups,the observation group included 31 patients and received breast-conserving surgery,and the control group included 26 patients and received modified radical mastectomy.Now we compare the therapeutic effect between the observation group and the control group in this paper.Results：①There were significant differences in operation time,hospitalization time,blood loss during surgery,incidence rate of postoperative complication,postoperative cosmetic results between the two groups.②There were no significant differences in local recurrence rate,distant metastasis rate between the two groups.Conclusion：The therapeutic effect is same between the breast-conserving surgery and the modified radical mastectomy for early-stage breast cancer,but the breast-conserving surgery is of shorter operation time and hospitalization time,less blood loss during surgery,lower incidence rate of postoperative complication,better postoperative cosmetic results,so this surgical treatment way is preferred for patients with early-stage breast cancer.