阿托品不同给药方式治疗有机磷中毒的疗效分析

Comparison of Different Methods of AdministeringAtropine in the Treatment of Organophosphate Poisoning

目的：探讨临床救治有机磷中毒的患者使用阿托品时采用不同给药方式的疗效差异。方法：将我院在2007年6月~2010年10月收治的101例急性有机磷中毒的患者随机分为三组,I组患者给予阿托品人工静脉推注;II组患者先给予阿托品人工静脉推注,患者达到阿托品化后采用微量泵给药;III组患者直接使用用微量泵给药,比较三组患者的疗效和并发症。结果：II组患者和III组患者的疗效优于I组患者,并发症低于I组患者,p〈0.05;III组患者阿托品化时间最长,与I组和II组比较,p〈0.05。结论：采用阿托品人工静脉推注,待患者阿托品化再给予微量泵给药,其疗效较好,不良反应少,患者阿托品化更稳定,值得在临床推广使用。

Objective：Clinical treatment of patients with organophosphate poisoning atropine administered in different ways when the difference in efficacy.Methods：In our hospital in June 2007~October 2010 treated 101 cases of acute organophosphate poisoning were randomly divided into three groups,I group were treated with intravenous injection of atropine and artificial;II patients are atropine artificial intravenous injection,the patient achieved using micro-pump after atropine administration;III patients directly with micropump delivery,three groups of patients compared the efficacy and complications.Results：Group II and III patients were more effective than group I patients,complications than group I patients,p 0.05;III longest of atropine in patients with Group I and II group,p 0.05.Conclusion：The use of artificial intravenous injection of atropine,atropine and then be given to patients with micro-pump delivery,the better effect,adverse reactions,patients with atropine is more stable,it is in clinical use.