氨基末端B型利钠肽对肺栓塞患者病情的估测价值被引量：1

The Evaluation Value of NT-proBNP in Pulmonary Thromboembolism Patient

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摘要目的:探讨氨基末端B型利钠肽(NT-proBNP)在评价肺栓塞严重程度中的作用以及对肺栓塞患者病情的估测价值。方法:采用罗氏Elecsys2010电化学发光免疫分析仪对2009年1月～2010年4月期间在我院内科系统住院治疗的PTE患者及年龄与性别匹配的健康人群进行NT-proBNP测定,并用SPSS15.0软件包进行统计学处理。结果:非大面积PTE患者血清NT-proBNP水平与健康对照组间性比相比P>0.05,但次大面积及大面积PTE患者血清NT-proBNP水平要明显高于对照组及非大面积PTE组(P<0.01),且大面积PTE组NT-proBNP又明显高于次大面积PTE组(P<0.01)。结论:NT-proBNP的水平可以灵敏地反映PTE患者的栓塞面积及病情严重程度,是指导治疗的一项简便、灵敏的工具。 Objective：To investigate the NT-proBNP function in severe degree of pulmonary thromboembolism（PTE） and the evaluation value of NT-proBNP in PTE patient.Methods：The NT-proBNP of PTE patients who were treated in hospital in the range of 2009.1-2010.4 and healthy people was analyzed on the Roche Elecsys 2010 electrochemistries analyze.The result was processed by SPSS 15.0.Results：The phase ratio of NT-proBNP result of in-large area PTE group and healthy controlled group was not different in statistics（P0.05）,but the NT-proBNP result of meta-large area PTE group and large area PTE group was higher than healthy controlled group and in-large area PTE group（P0.01）.Otherwise,the NT-proBNP result of large area PTE group and large area PTE group was higher than meta-large area PTE group（P0.01）.Conclusions：The level of NT-proBNP could sensitively reflect the embolism area and severe degree of PTE patient.It was a simple and sensitive tool to guide treatment.

作者张学鹏王晓娟

机构地区首都医科大学附属北京朝阳医院检验科首都医科大学附属北京朝阳医院呼吸科

出处《中国医药导刊》 2012年第2期205-206,共2页 Chinese Journal of Medicinal Guide

关键词氨基末端B型利钠肽肺栓塞 NT-proBNP Pulmonary thromboembolism

分类号 R563.5 [医药卫生—呼吸系统]

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