社区获得性肺炎的病原学研究及耐药性分析

Etiology Study of Community-acquired Pneumonia and Drug Resistance

目的:了解我院南区社区获得性肺炎(CAP)的病原学特征及耐药情况,合理使用抗生素。方法:对205例符合CAP诊断标准的患者留取痰或血进行细菌培养,采用血清学方法检测血中肺炎支原体、肺炎衣原体、嗜肺军团菌抗体等非典型病原体。结果:193例细菌培养显示,病原分离阳性79例(40.9%);200例血清学检查,在非典型病原体感染中以肺炎支原体感染最为常见。结论:CAP的病原谱及其对药物敏感性的差异为临床合理使用抗生素提供了理论依据。

Objective：To learn the etiological characteristics and drug resistance of community-acquired pneumonia（CAP） in Southern District of Beijing Tongren Hospital,so as to provide evidence for empiric antibiotic therapy.Methods：Collect specimens of sputum or blood for bacterial culture from 205 patients who met the diagnostic criteria of community-acquired pneumonia,apply serological methods to detect Mycoplasma pneumoniae antibody,Chlamydia pneumoniae antibody and Legionella pneumophila antibody.Results：Pathogens isolated were 79 cases（40.9%） from 193 patients,in which Klebsiella pneumoniae ranks first,followed by Streptococcus pneumoniae;Mycoplasma pneumoniae is the most common in 200 cases of serological examination.The sensitive antibiotics for pathogens were identified.Conclusions：Based on the test of drug resistance,the pathogens sensitive antibiotics should be used for treatment of CAP patients.