珠海地区575名女性骨密度测定及骨质疏松症危险因素初析

BONE DENSITOMETRY AND RISK FACTORS ANALYSIS ON OSTEOPOROSIS IN 575 FEMALE POPULATION IN ZHUHAI

目的了解珠海地区女性骨密度和骨量分布情况以及影响骨质疏松症(OP)的危险因素。方法采用双能X线骨密度仪对珠海地区的575例女性进行骨密度检测,并对个人疾病史、生活习性及月经史进行调查,根据OP发生与否,进行单因素和多因素分析。结果女性骨密度和骨量呈现年龄分布趋势;单因素分析结果显示年龄、绝经年限、体重指数(BMI)、糖尿病、骨折以及慢性病对OP存在影响;多因素分析结果显示年龄和慢性病是OP发病的危险因素,而BMI是OP的保护因素。结论女性骨密度随年龄的增长、绝经年限的增加而逐步下降,而保持一定体型及体重,有利于骨密度的维持及提高;及时发现、治疗糖尿病、慢性病(如甲亢、风湿)等,对防治骨质疏松有积极作用。

Objective To investigate the distribution range of bone density and bone mass of female population in Zhuhai,and learn the risk factors of female osteoporosis（OP）. Methods BMD was measured with dual energy X ray absorptionmetry in 575 cases of women living in Zhuhai,and investigated their individual disease history,living habit and menstrual history.according to the detection result we divided into osteoporosis group and non-osteoporosis group,then carried out single factor and multiple factors analysis methods. Results Female bone density took on age distribution trend.Single factor analysis result indicated that age,menopause age range,BMI,diabetes,bone fracture history and chronic disease were the risk factors of osteoporosis.Multiple factors Logistic Regression result showed that age and chronic disease were the risk factors of OP,but BMI was the protective factor of OP. Conclusion The BMD of women with age and menopause increases gradually decline,while maintaining a certain size and weight,will profit to maintain and improve bone density;timely detection and treatment of diabetes,chronic diseases（such as hyperthyroidism,rheumatoid）,etc.has a positive effect to the prevention of OP.