摘要
目的用24h动态血压监测方法观察国产左旋氨氯地平的降压疗效及作用持续时间。方法选取符合入选条件的轻中度高血压病人82例,年龄(60.2±5.5)岁。每天服用左旋氨氯地平5mg,共8wk,于治疗前后分别监测24h动态血压。结果治疗后24h、白昼及夜间的收缩压、舒张压均值均有明显下降(P<0.01),而心率无明显变化(P>0.05);血压负荷值也明显减小(P<0.01);收缩压、舒张压谷峰比均>50%。结论国产左旋氨氯地平治疗高血压疗效显著,稳定性好,可持续24h。
Objective To evaluate the antihypertensive effect of Levamlodipine by 24 hour ambulatory blood pressure monitoring（ABPM）. Methods According to an open, self controlled design, 82 patients with mild to moderate essential hypertension aged （60.2±5.5） a were studied. They were given 5 mg once daily for 8 weeks. Ambulatory blood pressure monitoring （ABPM） was measured before and after treatment. Results After 8 weeks of Levamlodipine treatment, 24 hour, day and night SBP and DBP showed a significant reduction （P 〈 0.01）; SBP and DBP loads decreased obviously （P 〈 0.01）; Trough-to-peak ratios of both SBP and DBP were larger than 50%. No changed in heart rate was found （P〉 0.05）. Conclusion Levamlodipine once daily is effective and steady in the treatment of hypertension.
出处
《中国中医药现代远程教育》
2012年第3期71-72,共2页
Chinese Medicine Modern Distance Education of China
关键词
左旋氨氯地平
高血压
动态血压
Lcvamlodipinc
Hypertension
Ambulatory blood pressure
