中医药治疗跟痛症临床疗效的meta分析

Meta-analysis of Traditional Chinese Medicine on Calcaneodynia

目的:系统评价中医药疗法对跟痛症的疗效。方法:以单纯西医治疗对照,对中医药疗法治疗跟痛症的随机对照研究进行系统评价,数据采用专用软件RevMan4.2版进行统计分析。结果:29篇研究共有3157例患者满足纳入标准,Meta分析结果显示,OR=3.66,Z=10.05(P<0.00001),95%CI为(2.84,4.72),中医药疗法治疗跟痛症总有效率高于西医对照组。对其中两个亚组进行分析:中药熏洗疗法合并效应量OR=2.98,Z=4.83(P<0.00001),小针刀合并效应量OR=4.37,Z=3.39(P=0.0007),中药熏洗、小针刀治疗跟痛症总有效率均高于西医对照组。漏斗图提示存在部分发表偏倚。结论:以本meta分析结果为基础,中医药疗法治疗跟痛症较单纯西医有效,但由于纳入试验方法学质量较低,目前尚不能得出最终结论,需高质量的试验进一步证实。

Objective： To systematically review the efficacy of TCM treatments on calcaneodynia. Methods： Western medi- cine treatment was taken to be compared with TCM treatments on calcaneodynia in a systematic evaluation of randomized controlled trials （RCTs）. All data were analyzed using special software RevMan4.2. Results： A total of 29 RCTs involving 3157 patients were included. Meta-analysis showed that the efficiency of TCM treatments on calcaneodynia were better than western medicine control group （OR~ 3.66, Z=10.05 （P〈0.00001）, 95%CI （2.84,4.72）, P〈0.00001）,. Meta-anal- ysis of two subgroups showed that the efficiency in herbal washing group （OR= 2.98, Z= 4.83） and the small needle knife group （OR：4.37,Z=3.39） were better than western medicine control group （P〈0.00001 and P〈0.0007）. Funnel fig ure suggested the presence of part of the publication bias. Conclusion： The results of meta-analysis showed that the efficiency of TCM treatments on calcaneodynia is better than western medicine treatment. However, we cannot make a final con clusion due to the low quality of inclusion trials. Studies of higher methodological quality are to needed to confirm the con clusion.