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Preparation and self-assembly of amphiphilic polymer with aggregation-induced emission characteristics 被引量:16

Preparation and self-assembly of amphiphilic polymer with aggregation-induced emission characteristics
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摘要 An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells. An amphiphilic polymer bearing tetraphenylethene (TPE) moiety was synthesized by convenient reactions. The polymer exhibits unique aggregation-induced emission (AIE) characteristics and can self-assemble to size-tunable particles in DMF/water mixtures. The polymer nanoparticles can be used for cell imaging, which provides a potential stable fluorescent tool to monitor the distribution of drugs and bioconjugates in living cells.
出处 《Science China Chemistry》 SCIE EI CAS 2012年第5期772-778,共7页 中国科学(化学英文版)
基金 supported by the National Natural Science Foundation of China (20974028, 20974098, and 21174120) the National Basic Research Program of China (2009CB623605) the Research Grants Council of Hong Kong (603509, HKUST2/CRF/10, 604711, and N_HKUST620/11) B.Z.T. thanks the support from the Cao Guangbiao Foundation of Zhejiang University
关键词 两亲聚合物 自组装 发射特性 聚集 聚合物纳米粒子 诱导 制备 细胞成像 amphiphilic polymer, aggregation-induced emission, tetraphenylethene, self-assembly, cell imaging
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