高乌甲素超前镇痛对行扁桃体腺样体切除患儿苏醒期躁动及术后镇痛的影响

THE EFFECTS OF PREEMPTIVE ANALGESIA OF LAPPACONITINE ON RESTLESSNESS DURING ANALEPSIA AND POSTOPERATIVE ANALGESIA FOR CHILDREN UNDERGOING ADENOID REMOVAL

目的探讨高乌甲素超前镇痛对行扁桃体腺样体切除患儿苏醒期躁动及术后镇痛的影响。方法将60例1～2级择期行扁桃体腺样体切除术的患儿随机分为A、B两组,每组30例。A组在气管插管后、B组在手术结束时,静脉滴注高乌甲素0.15mg/kg。记录两组患儿的麻醉时间、拔管时间、苏醒期镇静-躁动(RASS)评分及术后4、6、8、24h视觉模拟评分(VAS),并记录不良反应。结果两组患儿麻醉时间、拔管时间比较均无统计学意义(P>0.05);A组患儿RASS评分及术后4、6、8、24hVAS评分均低于B组(P<0.01);两组均无明显的不良反应。结论高乌甲素0.15mg/kg超前镇痛可以提高行扁桃体腺样体切除患儿苏醒期质量,抑制苏醒期躁动,并产生较好的术后镇痛效果,且无明显的不良反应。

Objective To explore the effects of preemptive analgesia of lappaconitine on restlessness during analepsia and postoperative analgesia for children undergoing adenoid removal.Methods 60 cases of adenoid removal at Grade1-Grade 2 were randomly divided into Group A and Group B with 30 cases in each group.0.15 mg/kg of lappaconitine was given to group A after tracheal intubation and to Group B after operations.The time of anaesthesia and intubation,the RASS scores of calmness and restlessness and the visual simulation scores 4,6,8 and 24 hours after operations as well as the side effects were all recorded.Results No sihnificant differences were found in the time of anaesthesia and intubation（P〈0.05）.The RASS scores 4,6,8 and 24 hours after operations in Group A were found lower than those in Group B（P〈0.01）.No side effects were found in both group.Conclusion The preemptive analgesia of 0.15 mg/kg of lappaconitine can improve patients＇ life quality during analepsia,inhibit restlessness and reduce postoperative analgesia for children undergoing adenoid removal without any side effects.