二尖瓣脱垂患者血清和淋巴细胞内钙、镁含量的探讨

CALCIUM AND MAGNESIUM DEFICIENCY IN PATIENTS WITH MITRAL VALVE PROLAPSE

对100例经听诊和超声心动图证实的二尖瓣脱垂患者血清和淋巴细胞内钙、镁含量进行测试。结果显示,患者淋巴细胞和血清钙、镁含量分别显著低于对照组(P<0.01),患告不仅缺镁、而且亦缺钙。延长的PEP/LVET和阳性Chvosteck征仅与淋巴细胞钙降低水平有关(P<0.01)。患者缺镁原因不明,钙的缺乏可能与长期严重缺镁导致获得性甲状旁腺功能低下有关。对伴有钙、镁含量降低的二尖瓣脱垂患者给予补充治疗也许是一种合理有效的措施。

Serum (S) and lymphocyte (L) calcium (Ca)and magnesium(Mg)levels were measured in 100 patients with mitral valve prolapse (MVP) diagnosed by auscultation and echocardiogram. S and L cations (Ca, Mg) in patients compared with controls were significantly lower(p<0.01). However, increased PEP/LVET and positive Chvostek's sign were related to the reduction of L Ca only. It is suggested that MVP patients not only have Mg, but also Ca deficiency. The mechanism of Mg deficiency is not known, but the decrease in Ca may be due to acquired parathyroid insufficiency, as a result of severe and prolonged hypomagnesemia. Supplemental therapy for MVP patients with Ca and Mg deficiency might be a rational and effective measure.