脑梗死后患者认知功能障碍的多因素相关研究

目的对脑梗死后患者发生认知功能障碍(VCI)的相关因素进行探讨。方法选择脑梗死患者156例采用CT或MRI明确患者病灶部位、测定病灶体积,分别记录患者的年龄、性别、受教育程度以及是否有高血脂、高血压和糖尿病的病史。使用MOCA与HAMD评定患者的认知功能和日常生活活动能力。结果根据MOCA表筛查发现高龄、教育程度低、高血压、糖尿病、多次梗死、多发病灶、脑萎缩患者组多于对照组组。结论认知功能障碍与发病的部位及病灶体积大小有关,同时高龄、受教育程度低、长期酗酒、高血压、糖尿病患者发生认知障碍的概率更高一些。

Objective To explore the related factors between cognitive disturbance and cerebral infarction.Methods Using CT or MRI to classify 156 cases,record their age,gender,education level,smoking,drinking and whether there is high blood lipids,hypertension and diabetes history.Results According to the MOCA table,temporal lobe,parietal lobe,occipital lobe occurs between P0.05;the cerebellum and brainstem infarction and age,low education,hypertension,diabetes,multiple infarction,cerebral atrophy in patients with multiple lesions.Conclusion Cerebral infarction can induce cognitive disturbance with various quality.