泰山散瘀膏抗炎镇痛作用的实验研究

Taishan Sanyu Ointment Experimental Study on Anti-inflammatory and Analgesic Effect

目的:研究泰山散瘀膏的抗炎镇痛作用。方法:取小鼠32只,随机分为致炎液实验组及致炎液对照组、冰醋酸实验组及冰醋酸对照组,每组8只,利用致炎液建小鼠耳廓肿胀模型,观察泰山散瘀膏的抗炎作用;采用小鼠醋酸扭体法研究泰山散瘀膏的镇痛作用。结果:泰山散瘀膏能显著降低小鼠耳廓肿胀程度,显著抑制冰醋酸所知疼痛后的扭体次数。结论:泰山散瘀膏具有明显的抗炎阵痛作用。

Objective ：To study the anti-inflammatory arid analgesic effects of Taishan san yu ointment.Methods ：32 mice were randomly divided into 4 groups. Empirical groups contained inflammation-inducing liquid group and glacial acetic acid group. In control groups, inflammation- inducing liquid group and glacial acetic acid group were also included. There were 8 mice in each group. The model of mouse auricle swelling was made up by inflammation-inducing liquid and used to observe the anti-inflammatory effect of Taishan san yu ointment. The method of acetic acid writhing used on the mice was adopted to research the analgesic effect of Taishan san yu ointment.Results ：Taishan san yu ointment can markedly lower the degree of mouse auricle swelling and also can remarkably reduce writhing frequency which is induced by glacial acetic acid.Conclusion ：Taishan san yu ointment has significant effect in anti-inflammation and analgesia.