妇康片联合中药治疗80例更年期功血疗效探讨

Norlutin Tablets Combined with Traditional Chinese Medicine Treatment of 80 Cases of Treatment of Climacteric Dysfunctional Uterine Bleeding

目的:比较妇康片联合中药和妇康片联合雄激素治疗更年期功能性子宫出血的临床效果。方法:将80例确诊为更年期功能性子宫出血的患者随机分为妇康片联合中药治疗组40例,妇康片联合雄激素对照组组40例,比较两组患者的止血效果、贫血改善、月经周期及经量恢复情况以及副反应,并观察治疗后子宫内膜转归及自然绝经情况。结果:A组治疗更年期功能性子宫出血效果显著,突破性出血少,复发少,贫血亦大有好转,副反应小;B组治疗更年期功血效果肯定,但治疗过程中出现经间突破性出血及转氨酶升高者多,贫血无明显改善,易复发。两组比较差异有统计学意义(P<0.05)。结论:妇康片联合中药治疗更年期功血效果明显,副作用少,值得临床推广应用。

Objective ：To compare the clinical effects between the norlutin tablets combining the traditional Chinese medicine and norlutin tablets combining the androgen in the treatment of perimenopausal functional uterine bleeding. Methods ：A total of 80 cases patients, who had been diagnosed as the perimenopausal functional uterine bleeding, were at random divided into the norlutin tablets combining traditional chinese medicine group （group A） of 40 cases and the norlutin tablets combining androgen group （group B） of 40 cases.The hemostasis effects, anemia improvement, menstrual cycles, recovery of menstruation amount and side reactions in two groups were compared, then observing the outcome of endometrium and details of natural menopause.Results ：The curative effect in the treatment of perimenopausal functional uterine bleeding was obvious with less breakthrough bleeding and recurrence, large improvement in anemia and slight side reaction in Group A. The curative effect in the treatment of perimenopausal functional uterine bleeding was sure in Group B, but the breakthrough bleeding occurred during the menstruation period and the transaminase went up for many people without obvious improvement in anemia and it was easy to recur. The differences between two groups bad statistical significance （P〈0.OS）.Conclusion ： The norlutin tablets combining traditional chinese medicine in the treatment of perimenopausal functional uterine bleeding had obvious curative effect with less side reactions, which is valuable for the clinical popularization and application.