肺动脉高压的药物治疗

Medication of Pulmonary Artery Hypertension

肺动脉高血压是以肺小动脉血管重构为特征的严重的肺循环疾病。近年来随着对肺动脉高压发病机制认识地提高,针对肺动脉高压的发病各环节的治疗,即靶向治疗取得了进展。在靶向治疗基础上,为降低单一药物的副作用及协同药物间的相互作用,联合用药成为肺动脉高压临床常用的治疗手段。

Pulmonary arterial hypertension is a kind of serious pulmonary circulation disease which characterized by small pulmonary artery reconstruction. With the improvement of understanding of the pathogenesis of pulmonary hypertension, the treatment targeting at specific parts of the disease pathways, the targeted therapy has been improved in recent years. On the basis of targeted therapy, for the reduction of the single medicine＇s side-effects and for the coordination of medicines interaction, the combination of medicines is action, the combination of medicines is commonly used in pulmonary hypertension clinical treatment.