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中药熏洗联合甲硝唑在滴虫性阴道炎中的疗效研究 被引量:10

Efficacy of Chinese herb fumigation combined with metronidazole in treatment of Trichomonas vaginitis
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摘要 目的为提高临床治疗效果,探索中药熏洗联合甲硝唑治疗滴虫性阴道炎的临床应用价值。方法选择2011年1-6月妇产科门诊进行治疗的56例滴虫性阴道炎患者,机械抽样随机将其中36例分为观察组,采取中药熏洗联合甲硝唑治疗;余者分为对照组,采取甲硝唑治疗。结果观察组控制率为100.0%,对照组控制率为80.0%;两组有效率差异无统计学意义,观察组痊愈率显著高于对照组(P<0.05),而无效率显著低于对照组(P<0.05);两组治疗费用差异无统计学意义,观察组症状缓解时间(5.2±1.4)d,痊愈时间(6.4±1.6)d,对照组的症状缓解时间(8.3±2.2)d,痊愈时间(10.4±1.8)d,两组症状缓解及痊愈时间差异有统计学意义(P<0.05)。结论中药熏洗联合甲硝唑治疗滴虫性阴道炎,可显著提高治疗效果,缩短治疗周期,但并未增加治疗费用。 OBJECTIVE To improve the clinical treatment effect and explore the clinical value of the application of Chinese herb fumigation combined with metronidazole in treatnment of Trichomonas vaginitis. METHODS A total of 56 Trichomonas vaginitis patients who enrolled in the outpatient department from Jan 2011 to Jun 2011 were chosen as the research objects; hy means of the mechanical sampling, 36 patients were randomly randomly divided into the observation group, the observation group was treated with the herb fumigation combined with metronidazole; the rest of the patients were set as the control group which was treated with metronidazole. RESULTS The control rate of the observation group was 100.0%, and the control rate of the control group was 80.0%; there was no significant difference in the efficiency between the two groups; the cure rate was significantly higher in the observation group than in the control group (P〈0.05), but the inefficient rate was significantly lower than that of the control group (P〈0.05); there was no statistical difference in the treatment cost between the two groups, the time of symptom relief in the observation group was (5. 2±l. 4)d and the recovery time was (6.4±1.6)d, while the time of symptom relief time in the control group was (8.3±2.2)d, and the recovery time was (10.4±1.8)d, there were statistical differences in both the symptom relief time and the recovery time (P〈0.05). CONCLUSION Chinese herb fumigation combined with metronidazole in treatment of Trichomonas vaginitis can significantly improve the therapeutic effect and shorten the treatment cycle without increasing the cost of treatment.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2012年第10期2118-2119,共2页 Chinese Journal of Nosocomiology
关键词 中药熏洗 甲硝唑 滴虫 阴道炎 Chinese herbal fumigation and washing Metronidazole Trichomonas Vaginitis
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  • 1谢辉,王雅静,帖超男,廖琳,刘佩娜.Chelex-100法及酚氯仿法提取阴道毛滴虫DNA的比较[J].四川动物,2004,23(4):338-340. 被引量:2
  • 2World Health Organization. An overview of selected curable sexually transmitted diseases,In World Heath Organization,Global program on AIDS[R]. Geneva,Switzerland:World Health Organiza- tion, 1995 : 2 - 27.
  • 3Sobel J, Nagappan V, Nyirjesy P. Metronidazole-resistant vaginal trichomoniasis-an emerging problem [ J ]. N Engl J Med, 1999, 341:292 -293.
  • 4Snipes LJ,Gamard PM,Narcisi EM,et al. Molecular epidemiology of metronidazole resistance in a population of Trichomonas vaginalis clinical isolates[ J]. J Clin Microbiol,2000,38:3004 - 3009.
  • 5Upcroft JA, Upcroft P. Drug susceptibility testing of anaerobic protozoa [ J ]. Antimicro Agents Chemotherapy, 2001,45 :1810 -1814.
  • 6Xiao JC, Xie LF, Fang SL, et al. Symbiosis of Mycoplasma hominis in Trichomonas vaginalis may link metronidazole resistance in vitro[ J]. Parasitol Res,2006,100( 1 ) : 123 - 130.
  • 7Katiyar Sk, Visvesrara GS, Edlind TD. Comparisons of ribosomal RNA sequences from arnitochondrial protozoa: implications for processing, mRNA binding and paromomyin suscetibility [ J ]. Gene, 1995,152:27 - 33.

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  • 1王玉香,张吉金.哈荔田教授妇科病外治法经验琐谈[J].新中医,1995,27(1):6-6. 被引量:4
  • 2Diba K, Namaki A, Ayatolahi H, et al. Rapid identification ofdrug resistant Candida species causing recurrent vulvovaginal candidiasis [J]. Med Mycol J, 2012,53 (3) : 193-198.
  • 3Watson CJ, Pirotta M, Myers SP. Use of complementary and alternative medicine in recurrent vulvovaginal candidiasis-re- sults of a practitioner survey [J]. Complement Ther Med, 2012,20(4) :218- 221.
  • 4Murina F, Graziottin A, Felice R, et al. Short-course treat- ment of vulvovaginal candidiasis: comparative study of flucon- azole and intra-vaginal fenticonazole [J]. Minerva Ginecol, 2012,64(2) :89-94.
  • 5Witt A, Kaufmann U, Bitschnau M, et al. Monthly itracon- azole versus classic homeopathy for the treatment of recurrent vulvovaginal eandidiasis: a randomised trial[J]. BJOG,2009, 116(11) : 1499-505.
  • 6Donders GG, Van CK, Bellen G, et al. Predictive value for preterm birth of abnormal vaginal flora, bacterial vaginosis and aerobic vaginitis during the first trimester of pregnancy [ J ]. B JOG, 2009,16 (10) : 431 - 432.
  • 7Bachmann LH, Hobbs MM, Sefia AC, et al. Trichomonas vaginalisgenital infections: progress and challenges [J]. Clin Infect Dis,2011,53 (Suppl 3): S160-S172.
  • 8Rabiee S,Bazmani A,Matini M, et al. Comparison of resistant andsusceptible strains of trichomons vaginalis to metronidazole using PCRmethod [ j]. Iran J Parasitol, 2012,7 (3): 24-30.
  • 9Goodhew EB, Secor WE. Drug library screening against metronida-zole-sensitive and metronidazole-resistant Trichomonas vaginalisisolates [j]. Sex Transm Infect, 2013, 89 (6): 479-484.
  • 10Bosserman EA, Helms DJ, Mosure DJ, et al. Utility of antimicro-bial susceptibility testing in Trichomonas vagi nalis-infected womenwith clinical treatment failure [J]. Sex Transm Dis, 2011,38(10): 983-987.

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