全国1～14岁人群乙型肝炎病毒表面抗原阳性危险因素分析

Analysis on Risk Factors of Hepatitis B Virus Surface Antigen Prevalence among People Aged 1-14 Years in China

目的探讨全国(未包括香港、澳门特别行政区和台湾地区,下同)1～14岁人群乙型肝炎(乙肝)病毒表面抗原[Hepatitis B Virus(HBV)Surface Antigen,HBsAg]阳性的危险因素。方法对2006年全国人群乙肝血清流行病学调查中,1～14岁人群HBsAg阳性者的相关因素进行流行病学分析。结果全国1～14岁人群中,男性HBsAg阳性的风险是女性的1.31倍;5～14岁人群HBsAg阳性的风险是1～4岁人群的1.42倍;农村人群HBsAg阳性的风险是城市人群的1.61倍;家庭内有HBsAg阳性人群的HBsAg阳性的风险是家庭内无HBsAg阳性人群的4.10倍;未接种乙肝疫苗(Hepatitis B Vaccine,HepB)人群HBsAg阳性的风险是接种HepB人群的3.06倍。结论坚持以新生儿接种HepB为主的预防控制策略,加强预防控制乙肝的健康教育,减少HBV传播风险。

Subject Exploring risk factors of hepatitis B virus surface antigen （I-IBsAg） prevalence among people aged 1 to lg years in China. Method Using the national hepatitis B serosurvey data in 2006, we analyzed the risk factors of HBsAg prevalence among people aged 1 to 14 years. Results Among people aged 1 to 14 years in China, the male had high risk than female （Odds Ratio, OR=1.31）, children aged 5 to 14 years had higher risk than children aged 1 to 4 years （OR=1.42）, children living in rural had higher risk than children living in urban （OR=l.61）. The children who had HBsAg positive persons in their families had higher risk than who had not HBsAg positive persons in their families （OR=4.10）. The unvaccinated chiledren had higher risk than vaccinated children （OR=3.06）. Among the eastern, central and western regions, tilers were no difference. Conclusion We should adhere to the prevention strategy of neonatal hepatitis B vaccine immunization continuously, and strengthen the management of the health education of hepatitis B prevention and control and reduce the risk of hepatitis B transmission.