异时性尿路上皮移行细胞癌(附10例报告)

Clinical features of metachronous urothelial TCC (report of 10 cases)

目的 探讨异时发生的尿路上皮肿瘤的临床特点 ,提高尿路上皮肿瘤的治愈率。 方法 回顾性分析 36 8例尿路上皮肿瘤资料 ,其中异时性上尿路肿瘤 5例 (2 % ) ,间隔时间 6～ 48个月 ;异时性膀胱肿瘤 5例 (10 % ) ,间隔时间 4～ 2 4个月。 结果 3例异时性上尿路肿瘤死亡 ,其中 1例为原位癌 ,另 2例分别为G3 多发和G1单发肿瘤 ,余 2例及 5例异时性膀胱肿瘤均为无瘤存活。 结论 异时性膀胱肿瘤的发生率明显高于上尿路肿瘤 ,发生肿瘤的异时性对患者预后有一定影响 ,加强肿瘤术后监测是提高患者生存率的重要手段之一。

Objective To investigate the features of urothelial TCC and its metachronous characte ristics. Methods 368 cases of urothelial TCC were analysed retrospectively, among these there were 5 cases of metachronous upper urinary tract TCC (2%) and 5 cases of metachronous urinary bladder TCC (10%). Results 3 cases of metachronous upper urinary tract TCC died of the malignancies. The rest 7 are surviving and tumor free. Conclusions Metachronous urinary bladder TCC occurs more than metachronous upper tract TCC. Metachronous malignancy plays an important role in patient’s prognosis. Postoperatively monitoring is very important in order to improve the patients' outcome.