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阿托伐他汀对急性冠状动脉综合征患者血浆B型钠尿肽水平的影响 被引量：6

Effect of atorvastatin on BNP levels in patients with acute coronary syndrome
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摘要 目的探讨阿托伐他汀对急性冠状动脉综合征（ACS）患者血浆B型钠尿肽（BNP）水平的影响。方法选择青岛大学医学院第二附属医院2010年12月至2011年8月收治的ACS患者80例，随机分为观察组和对照组，每组40例，在控制饮食的同时观察组加用阿托伐他汀40mg，每日1次口服，治疗12周。比较两组患者治疗前后BNP水平。结果两组患者BNP水平均明显下降（P〈0．05），且观察组比对照组下降更为显著。结论阿托伐他汀能够明显降低患者的BNP水平，改善预后。 Objective To investigate the effect of atorvastatin on B-type natriuretic peptide （BNP） levels in patients with acute coronary syndrome. Methods Eighty patients with ACS hospitalized in our hospital from December 2010 to August 2011 were randomly divided into two groups：control group （ n = 40） and treatment group （ n = 40）. Patients in the treatment group received atorvastatin 40 mg per day for twelve weeks on the basis of diet control. BNP levels were compared in the two groups before and after treatment. Results After the treatment, BNP levels of the two groups were obviously decreased （P 〈 0. 05）, and was decreased more significantly in treatment group. Conclusions Atorvastatin can decrease the BNP level and improve the prognosis of patients with ACS.
作者 周美丽 赵青 任金玲
机构地区 青岛大学医学院第二附属医院急诊内科
出处 《中国实用医刊》 2012年第11期35-36,共2页 Chinese Journal of Practical Medicine
关键词 阿托伐他汀 急性冠状动脉综合征 B型钠尿肽 Atorvastatin Acute coronary syndrome B-type natriuretic peptide
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献7

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共引文献25

同被引文献39

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引证文献6

二级引证文献32

中国实用医刊
2012年 第11期

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