新一代冠状动脉支架的研发方向——“内皮友好型”药物支架
被引量:2
摘要
药物洗脱支架(DES)是经皮冠状动脉介入治疗(PCI)中的里程碑,可减少支架内再狭窄的发生,降低再次血运重建率。然而,DES的这种作用却是一把双刃剑。支架本身及其表面的涂层相对人体来说是一种异物,可引起植入部位的炎性反应和超敏反应。
出处
《上海医学》
CAS
CSCD
北大核心
2012年第3期250-252,共3页
Shanghai Medical Journal
参考文献13
-
1MCCORMICK C. The search for endothelium friendly stents [J]. Med Device Technol, 2007, 18(3): 30, 32-33.
-
2YANG W, GE J, LIU H, et al. Arsenic trioxide eluting stent reduces neointima formation in a rabbit iliac artery injury model[J]. Cardiovase Res, 2006, 72: 483-493.
-
3BYRNE R A, KASTRATI A, TIROCH K, et al. 2-year clinical and angiographic outcomes from a randomized trial of polymer-free dual drug-eluting stents versus polymer-based Cypher and Endeavorl-correeted] drug-eluting stents[J]. J Am Coll Cardiol, 2010, 55(23) : 2536-2543.
-
4SILBER S, DAMMAN P, KLOMP M, et al. Clinical results after coronary stenting with the Genous? Bio-engineered R stent?: 12-month outcomes of the e-HEALING (Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth) worldwide registry [ J ]. EuroIntervention, 2011, 6 ( 7 ) : 819-825.
-
5GRANADA J F, INAMI S, ABOODI M S, et al. Development of a novel prohealing stent designed to deliver sirolimus from a biodegradable abluminal matrix [J]. Circ Cardiovasc Interv, 2010, 3(3): 257-266.
-
6GE J, QIAN J, WANG X, et al. Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteries [J]. Catheter Cardiovasc Interv, 2007, 69(2) : 198-202.
-
7WINDECKER S, SERRUYS P W, WANDEL S, et al. Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non-inferiority trial[J]. Lancet, 2008, 372(9644) : 1163-1173.
-
8KARJALAINEN P P, ANNALA A P, YLITALO A, et al. Long-term clinical outcome with titanium-nitride-oxide-coated stents and paclitaxel-eluting stents for coronary revascularization in an unselected population [J]. Int J Cardiol, 2010, 144(1): 42-46.
-
9MENG S, LIU Z, SHEN L, et al. The effect of a layer-by-layer chitosan-heparin coating on the endothelialization and coagulation properties of a coronary stent system [ J ]. Biomaterials, 2009, 30(12): 2276-2283.
-
10TSUJINO I, AKO J, HONDA Y, et al. Drug delivery via nano-, micro and macroporous coronary stent surfaces[J]. Expert Opin Drug Deliv, 2007, 4(3): 287-295.
同被引文献30
-
1韩雅玲.中国经皮冠状动脉介入治疗指南2012(简本)[J].中国医学前沿杂志(电子版),2012,4(12):50-59. 被引量:133
-
2蔡军,陆峥.冠心病患者生活质量研究进展[J].上海精神医学,2002,14(2):111-113. 被引量:18
-
3莫云秋,王强,方显明,何贵新.安心颗粒对冠心病心绞痛患者超敏C-反应蛋白的影响[J].广州中医药大学学报,2005,22(5):341-343. 被引量:2
-
4中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量:5228
-
5何奇明,仝其广.危险因素和血运重建治疗对冠心病预后的影响[J].中国医药导刊,2007,9(3):197-199. 被引量:1
-
6潘三葱,秦中胜,韩麦丰,王丽.急性冠脉综合征患者血浆D-二聚体和vWf的变化及临床意义[J].实用心脑肺血管病杂志,2007,15(6):417-418. 被引量:1
-
7Morice M C, Serruys P W, Sousa J E, et al. A randomized compar- ison of a sirolimus-eluting stent with a standard stent for coronary revascularization [ J ]. N Engl J Med, 2002,346 ( 23 ) : 1773.
-
8Moses J W, Leon M B, Popma J J, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coro- nary artery[J]. N Engl J Med,2003,349(14) :1315.
-
9Finn A V, Kolodgie F D, Harnek J, et al. Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus or paclitaxel-eluting stents [ J ]. Circulation, 2005,112 (2) :270.
-
10Daemen J, Wenaweser P,Tsuchida K, et al. Early and late coro- nary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice : data from a large two-institu- tional cohort study [ J 1. Lancet,2007,369 (9562) :667.
引证文献2
-
1卢健棋,何贵新,潘朝锌,温志浩,张以昆,方显明,郭太华,潘爱萍,吴海珊.安心颗粒联合替罗非班对急性心肌梗死PCI术后患者临床疗效的研究[J].中国中药杂志,2014,39(5):920-924. 被引量:32
-
2张安宁,张海涛,孙津津,黄丛春,罗惠兰.不同程度冠状动脉病变患者介入治疗前后生活质量变化[J].中国循证心血管医学杂志,2016,8(6):720-724. 被引量:9
二级引证文献41
-
1何贵新,谭炜,卢健祺,方显明,陈远平.安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究[J].广西医科大学学报,2014,31(6):938-941. 被引量:1
-
2谭炜,何贵新.安心颗粒联合血栓抽吸对急诊冠脉介入术后心肌灌注影响的研究[J].南京中医药大学学报,2015,31(1):13-16. 被引量:9
-
3伍裕.中医治疗对心肌梗死患者介入治疗后心肌再灌注和心功能的改善作用[J].中国医药导报,2015,12(4):129-132. 被引量:21
-
4刘远萍,郝亚荣.Firebird支架联合替罗非班用于急性心肌梗死中的疗效及安全性[J].心血管康复医学杂志,2015,24(5):557-561. 被引量:2
-
5张景文,程王生.冠脉内应用替罗非班在急性心肌梗死急诊经皮冠状动脉介入术中的效果观察[J].中国当代医药,2016,23(18):69-71. 被引量:1
-
6黄向荣.基层医院采用国产尿激酶静脉溶栓治疗急性心肌梗死72例效果分析[J].中国当代医药,2016,23(24):118-120. 被引量:2
-
7王京,高燕,王晨霞.安心通络方联合替罗非班对急性心肌梗死PCI术后血浆sICAM-1及心肌微循环的影响[J].中医药导报,2016,22(19):91-93. 被引量:7
-
8赵丹.替罗非班对急性心肌梗死后白介素-17的表达及其与室性心律失常的相关性分析[J].中西医结合心脑血管病杂志,2016,14(22):2651-2654. 被引量:6
-
9潘庆丽,霍本良,王立旗,吕长泳,姜威峰,李伟华.替罗非班在急性心肌梗死急诊PCI中的应用效果分析[J].中国循证心血管医学杂志,2017,9(5):609-611. 被引量:24
-
10黄颖欣,吴毅明,江美芝.早期康复运动联合血栓通注射液对AMI患者术后康复疗效及proBNP影响[J].辽宁中医药大学学报,2017,19(6):103-106. 被引量:6
-
1杨小勇.利福平致急性肾功能衰竭1例报告[J].右江民族医学院学报,2003,25(2):248-248.
-
2白爱林,谢蜀生,龙振洲.成年小鼠皮肤移植耐受诱导的实验研究[J].中国免疫学杂志,1994,10(5):274-277. 被引量:15
-
3张江霖.雌激素是更年期的双刃剑[J].中国家庭医生,2014(19):14-14.
-
4宋茂力,邹小明.浅谈腹腔引流的选择性放置[J].国际外科学杂志,2013,40(1):1-3. 被引量:2
-
5陈良富,柳洁,李莉,张雪梅.腹膜炎大鼠肥大细胞及间皮的形态变化[J].解剖学杂志,2004,27(5):479-481. 被引量:1
-
6P.M.Markus,H.Becker,张伟杰.肝细胞移植——从设想到临床应用[J].德国医学,2000,17(2):69-70.
-
7方开云,安裕文.小儿肌松药致超敏反应二例[J].中华麻醉学杂志,2005,25(6):477-477. 被引量:1
-
8韩晓华,温冠清.褪黑激素对严重烧伤大鼠迟发型超敏反应的影响[J].中国临床康复,2006,10(32):89-91.
-
9金士翱.麻醉中的变态反应[J].中华麻醉学杂志,1996,16(11):568-569. 被引量:4
-
10邹淑娥,徐毅君,尹文娟.鱼精蛋白速发超敏反应1例[J].山东医药,2006,46(25):15-15.