四逆汤提取工艺的筛选

Screening of Abstraction Technology for Sini Decoction

四逆汤是中医临床上用于治疗亡阳厥逆证的传统有效方剂 ,由附子、甘草、干姜三味药组成。提取工艺的合理性对药物疗效的发挥起着关键性的作用。本研究以乌头碱类生物碱的含量作为指标 ,用高效液相色谱法作为检测方法 ,经过正交实验筛选 ,证明了 :(1)全方的提取方法宜采用单煎混合法 ;(2 )提取液的除杂最好采用超滤法 ;(3)

ion technology is very important to the curative effect.The content of aconitine_type alkaloids was taken as a criterion and high efficiency liquid chromatography as the analyzing method.Screening with orthogonal experimental method showed that:(1)The best abstraction technology for Sini Decoction is by decocting the drugs separately and then mixing;(2)The best trash extraction method is ultrafilter;(3)The extracting solution of Rhizoma Zingiberis should be kept after the volatile oil was abstracted.