郑州地区学龄儿童肥胖特征及糖代谢的调查分析

Investigation of glucose metabolism and obesity in school-age children in Zhengzhou city

目的了解郑州地区学龄儿童肥胖症的患病情况并分析相关影响因素。方法通过报纸招募7～14岁肥胖儿童来我院检查,对于符合肥胖症标准的422例儿童填写统一设计的表格并进行体检和实验室检查。结果郑州地区学龄肥胖症的儿童,糖尿病、IGR、IR、良性黑棘皮病、高血压的患病率分别为2.4%、20.3%、43.1%、80.1%、35.9%。多元线性逐步回归分析发现,出生时体重和WC与BMI相关(P<0.01),性别、年龄、WC、FPG与FIns水平相关(P<0.01)。结论郑州地区肥胖儿童的糖调节障碍、IR、高血压的患病率高。儿童的肥胖程度呈现随年龄增加逐渐加重趋势。加强对肥胖儿童的筛查与管理,对防止成年后代谢疾病的高发具有重要意义。

Objective To investigate the status of children adiposity at school age, and to analysis their related factors. Methods We advertised through the press, and recruited obese children aged 7- 14y to our hospital. All the children meeting the diagnostic criteria for obesity filled out the unifiable form and had a physical examinations and laboratory tests. Results The prevalence of diabetes, impaired glucose regulation, insulin resistance, benign acanthosis nigricans and hypertension were 2.4 %, 20.3%,43.1 %, 80.1%, 35.9% respectively among adolescents with adiposity in Zhengzhou city. By mukiple linear stepwise regression analysis, we found that birth weight and waist circumference were related to body mass index（P〈0.01）, Meanwhile sex, age, waist, fasting plasma glucose were related to fasting serum insulin level （P〈0. 01）. Conclusions The prevalence of glucose dysregulation, insulin resistance and hypertension performance among obese children were increased in Henan province. The degree of obesity in children tended to increase with increasing age gradually. Strengthened screening and management of obese children are very helpful to prevent the high incidence of metabolic disease after being adults .