摘要
目的了解9种呼吸道病原体的IgM抗体检测结果及流行情况。方法使用9种呼吸道病原体检测试剂(Pneumoslide IgM)检测2011年3月-2012年2月医院门诊与住院患者血清中呼吸道病原体:嗜肺军团菌血清1型(LP1)、肺炎支原体(MP)、Q热立克次体(COX)、肺炎衣原体(CP)、腺病毒(ADV)、呼吸合胞病毒(RSV)、流感病毒A(INFA)、流感病毒B(INFB)和副流感病毒1、2、3(PIVs)的检出情况及季节性变化。结果共检测1647份血清,410份阳性,阳性率为24.9%;流感病毒(INFs),包括INFA、INFB,为阳性率最高的病原体,阳性率为9.2%;居第2~5位的分别是RSV、PIVs、MP、LP1,阳性率依次为8.7%、5.4%、5.0%、2.1%;RSV与MP在3月的阳性率均为最高,分别为24.0%、19.2%;INFA夏季的阳性率最高,达16.8%,而INFB在1、2月份和7、8月份的阳性率均较高;LP1夏季的阳性率显著高于冬季(P=0.016);26~64岁年龄组患者的病原体阳性率高于≤25岁和≥65岁年龄组患者(P=0.001)。结论 INFs是引起呼吸道感染的最重要的病原体;应做好防范工作,在重点季节预防相应病原体的流行和传播。
OBJECTIVE To explore the detection and epidemiology of IgM of 9 species of respiratory tract pathogens.METHODS The serums of the hospitalized patients with respiratory tract infections caused by 9 pathogens were detected with pneumoslide IgM from Mar 2011 to Feb 2012,including Legionella pneumophila serogroup 1(LP1),Mycoplasma pneumonia(MP),Coxiella burnetii(COX),Chamydophila pneumonia(CP),Adenovirus(ADV),Respiratory syncytial virus(RSV),Influenza A(INFA),Influenza B(INFB),Parainfluenza 1,2 and 3(PIVs).RESULTS Of totally 1647 serum specimens detected,there were 410 positive with the positive rate of 24.9%;the influenza viruses(INFs),including INFA and INFB,were the dominant pathogens with the positive rate of 9.2%,the pathogens ranking the second place to the fifth place were RSV,PIVs,MP and LP1,the positive rates were 8.7%,5.4%,5.0%,and 2.1%,respectively;the positive rates of RSV and MP were 24.0% and 19.2% in March,which were the highest;the positive rate of INFA was the highest in summer,reaching up to 16.8%;the positive rate of INFB was relatively high in January,February,July and August;the qualified rate of LP1 in summer was higher than that in winter(P=0.016);the positive rate of the pathogens isolated from the patients aged from 26 to 64 years was higher than that of the pathogens isolated from the patients aged less than 25 years or more than 65 years(P=0.001).CONCLUSION INFs is the most predominant pathogen causing respiratory tract infections;it is necessary to make protection well done so as to prevent the prevalence and spread of the pathogens in peak seasons.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第12期2696-2698,共3页
Chinese Journal of Nosocomiology
关键词
呼吸道感染
成人
流行病学
病毒
军团菌
肺炎支原体
Respiratory tract infection; Adult; Epidemiology; Viruses; Legionella; Mycoplasma pneumonia