慢性阻塞性肺疾病急性加重期空腹血糖、糖化血红蛋白变化特点及意义

Characteristics and significance of fasting glucose and glycated hemoglobin changes in acute exacerbation stage of chronic obstructive pulmonary diseases

目的了解慢性阻塞性肺疾病急性加重期血糖、糖化血红蛋白的变化特点及临床意义。方法对慢性阻塞性肺疾病急性加重期(40例)、稳定期(40例)进行空腹血糖、糖化血红蛋白测定,与正常对照组(40例)分析比较。结果急性加重期组血糖明显高于稳定期组及正常对照组,差异有统计学意义(Р<0.05),糖化血红蛋白和空腹血糖之间未存在明显相关(P>0.05)。结论慢性阻塞性肺疾病急性加重期易发生急性高血糖反应,对疾病的预后不利。

Objective To understand the characteristics and significance of fasting glucose and glycated hemoglobin changes in the acute exacerbation stage of chronic obstructive pulmonary diseases.Methods The fasting glucose and glycated hemoglobin of the acute exacerbation stage（40 patients） and the stable stage（40 patients） of patients with chronic obstructive pulmonary diseases were tested and compared to the normal control group（40 patients）.Results The blood glucose of the acute exacerbation stage group was significantly higher than that of the stable stage group and the normal control group respectively,with statistically significant difference（Р 0.05）,but the glycosylated hemoglobin and fasting blood glucose were not significantly correlated（Р 0.05）.Conclusion Acute hyperglycemia is prone to occur in the acute exacerbation stage of chronic obstructive pulmonary disease,which is harmful to the prognosis of disease.