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绝经后妇女他汀类药物使用与新发糖尿病风险研究的评论 被引量:4

Comment on "Statin use and risk of diabetes mellitus in postmenopausal women in the Women′s Health Initiative"
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摘要 自1976年第一个他汀类药物美伐他汀(mevastatin)问世以来,他汀家族日益庞大,并在治疗及预防疾病领域取得了巨大的成功。他汀类药物是一种HMG-CoA还原酶抑制剂,减少胆固醇合成,早期作为一种降脂药为人们所熟知。1994年的4S研究首次明确了辛伐他汀调脂治疗在降低LDL-C的同时,可以显著降低血脂异常患者死亡率达30%,
作者 钟优 丁霞
出处 《中国心血管杂志》 2012年第3期222-223,共2页 Chinese Journal of Cardiovascular Medicine
关键词 妇女 绝经期 糖尿病 他汀类药物 Women Menopause Diabetes mellitus Statin
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参考文献3

  • 1Culver AL,Ockene IS, Balasubramanian R, et al. Statin use and risk of diabetes mellitus in postmenopausal women in the Women's Health Initiative. Arch Intern Med, 2012, 172: 144- 152.
  • 2Rajpathak SN,Kumbhani DJ, Crandall J, et al. Statin therapy and risk of developing type 2 diabetes : a meta-analysis. Diabetes Care, 2009,32 : 1924-1929.
  • 3Sattar N, Preiss D, Murray HM, et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet, 2010, 375:735-742.

同被引文献42

  • 1汶麦霞,田华,张倩蓉,郑小璞,饶坤睿,袁红.绝经对女性冠心病患者临床特征及危险因素的影响[J].西安交通大学学报(医学版),2012,33(3):321-323. 被引量:18
  • 2Jackson KC,Wohlers LM,Valencia AP,et al.Wheel running prevents the accumulation of monounsaturated fatty acids in the liver of ovariectomized mice by attenuating changes in SCD-1 content[J].Appl Physiol Nutr Metab,2011,36(6):798-810.
  • 3Sattar N,Preiss D,Murray HM,et al.Statins and risk of incident diabetes:a collaborative meta-analysis of randomised statin trials[J].Lancet,2010,375(9716):735-742.
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  • 5Mooradian AD.Dyslipidemia in type 2 diabetes mellitus[J].Nat Clin Pratc Endocrinol Metab,2009,5(3):150-159.
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  • 7Magkos F,Fabbrini E,Mohammed BS,et al.Estrogen deficiency after menopause does not result in male very-low-density lipoprotein metabolism phenotype[J].J Clin Endocrinol Metab,2010,95(7):3377-3384.
  • 8Freeman DJ,Norrie J,Sattar N,et al.Pravastatin and the development of diabetes mellitus:evidence for a protective treatment effect in the West of Scotland Coronary Prevention Study[J].Circulation,2001,103(3):357-362.
  • 9Keech A,Colquhoun D,Best J,et al.Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose:results from the LIPID trial[J].Diabetes Care,2003,26(10):2713-2721.
  • 10Shepherd J,Blauw GJ,Murphy MB,et al.Pravastatin in elderly individuals at risk of vascular disease(PROSPER):a randomised controlled trial[J].Lancet,2002,360(9346):1623-1630.

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