摘要
目的 :观察骨形成蛋白特异的细胞内信号转导分子Smad1在人牙胚发育过程中的表达变化 ,探讨Smad1在牙齿发育过程中的作用。方法 :制备人牙胚发育各期标本 ,免疫组化方法观察Smad1在人牙胚发育过程中的表达情况。结果 :Smad1在牙胚发育的不同时期均可见不同的时空表达模式。结论 :观察到Smad1信号分子在人牙胚发育过程中的表达 ,Smad1可能在牙胚各期的发育起一定的作用。
AIM: To investigate the expression of Smad 1 rotein in tooth germ development, to explore the function of Smad 1 during tooth germ development. METHODS: Using immunohistochemical staining after preparing specimens of every stage of human developing tooth germ. RESULTS: Smad 1 had its own specific temporal-spatial pattern during tooth germ development. CONCLUSION:The expression of Smad 1 gene in tooth germ development was detected. It suggests that Smad 1 may play a role in tooth germ development.
出处
《牙体牙髓牙周病学杂志》
CAS
2000年第2期78-80,共3页
Chinese Journal of Conservative Dentistry
基金
国家自然科学基金!(39870 789)