消痞通降汤治疗功能性消化不良的临床观察

Clinical Observation of Functional Dyspepsia Treated by Xiaopi Tongjiang Decoction

目的:观察中药消痞通降汤治疗寒热错杂型功能性消化不良的疗效。方法:采用随机、对照的观察方法,将120例患者分为对照组和治疗组,治疗组采用消痞通降汤,对照组采用吗丁啉治疗。经过4周治疗,采用临床症状积分法,观察功能性消化不良的上腹饱胀、早饱、嗳气、上腹疼痛等症状缓解情况。结果:经过治疗后,中药消痞通降汤可以明显改善上腹饱胀、早饱、嗳气、上腹疼痛、恶心、厌食、烧心、泛酸症状(P<0.01),尤其是早饱感、上腹痛、烧心、泛酸、嗳气的改善效果非常显著,疗效优于对照组(P<0.05),其总疗效也明显优于对照组(P<0.05)。结论:以辛开苦降法为组方原则的消痞通降汤对FD的临床症状评分和治疗的总有效率均明显高于吗丁啉对照组,有一定的疗效。

Objective：To explore the effect of Xiaopi Tongjiang Decoction on the treatment of Functional Dyspepsia.Methods：120 patients with functional dyspepsia were randomly divided into the experimental group（n=60）and the control group（n=60）.The experimental group was given Xiaopi Tongjiang Decoction,and the control group was only given Domperidone for 4 weeks.The improvement of clinical symptoms such as stomach burn,abdominal distention,upper abdominal pain and eructation were evaluated by clinical symptom score.Results：After 4 weeks＇ treatment,the abdominal symptom scores of both groups were significantly lower than those before the treatment（P0.05）,and the improvement of abdominal symptom score of control group was significantly lower than that of experimental group（P0.05）.Conclusion：Xiaopi Tongjiang Decoction is more effective in patients with functional dyspepsia than Domperidone.It deserves clinical expansion.