大段异体半关节置换远期疗效分析

Long-term Observation on Massive Retrieved Human Allografts

目的 :进一步了解大段异体半关节置换修复邻近关节的骨肿瘤切除的远期疗效。方法 :通过组织学及X线方法对其做一总结。结果 :大段异体半关节植入体内 10年其成骨替代仍不完全 ,骨吸收及骨形成仍在继续进行 ,新骨形成周围仍见到未被吸收的碎骨片和异物巨细胞聚积形成的肉芽肿。新骨形成不良区域被纤维结缔组织所填充。X线片提示关节间隙变窄 ,并有退行性变。异体半关节骨折、塌陷位于干骺端。结论 :大段异体半关节置换作为一种保肢手术方式有其优点 ,骨折及塌陷是因骨吸收大于骨形成 ,积极处理并发症异体半关节仍可保留于体内。

Objective: To know the results about massive human allografts reconstruction with defects after resection adjacence joints tumors.Method:followed up 10 patients by histology and radiography.Results:There are still apearing bone resorption and new bone formation in 10 years after massive human allografts.The pieces of un-resorpted bone and massive foreign gaint cells around the allografts bone can be seen in the radiography, the narrow space of the joints and degenerative change are shown.There are fractures and collapse in the metaphyseal end.Conclusion:The replacement of massive human allografts as a method of limb salvage is excellent.Fractures and collapes are caused by the bone resorption more than the bone formation.The complications have been managed by active and the massive human allografts still alive in body.