结石性胆囊胆汁厌氧菌的检测

Detection of bile anaerobic bacteria in patients with gallstone

目的 探讨不同种类厌氧菌在结石性胆囊胆汁中的分布及其临床价值。方法 对 6 7例结石性胆囊胆汁进行厌氧菌培养和自动检测分析。结果 各型厌氧菌的总检出率为 5 5 2 % (37/ 6 7) ,厌氧菌株主要以脆弱类杆菌为主 ,4例为专性厌氧。结论 胆囊结石的形成可能与厌氧菌感染存在联系 ;专性厌氧菌感染具有病史长 ,抗菌治疗效果差的特点。

Objective To detect bile anaerobic bacteria and their actiones in patients with gallstone. Methods Anaerobic bile culture was done by automatic detection system in 67 gallstone patients with cholecystectomy. Results The ratio of positive anaerobic bacteria culture was 55.2%(37/67), including 4 patients with obligate anaerobe bile culture positive only. B.fragilis was the main kind of anaerobic bacteria in bile. Conclusions There may have some connection between anaerobic infection and gallstone formation. The patients with obligate anaerobic bacteria positive only have a long term history of chronic cholecystitis and display no improvement of the clinical symptoms by antimicrobile treatments.