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冠心病伴胰岛素抵抗患者血清脂联素水平的研究

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摘要 目的探讨冠心病或伴胰岛素抵抗患者血清脂联素水平关系。方法选择标准冠心病患者155例,据稳态模式评估法评价胰岛素抵抗指数≥2.8,分冠心病无胰岛素抵抗组(CHD不伴IR)66例,冠心病伴胰岛素抵抗组(CHD伴IR)89例,对照组采用ELISA法测定脂联素水平健康者40例。结果血清脂联素水平,单纯冠心病组(9.52±0.89)μg/mL,冠心病伴胰岛素抵抗组(7.67±0.64)μg/mL明显小于对照组(14.93士1.54)μg/mL,存在差异有显著统计学意义(P<0.01);在单纯冠心病与冠心病伴胰岛素抵抗患者存在差异也同样具有统计学意义(P<0.05)。结论血清脂联素可能具有保护性作用,与胰岛素抵抗及冠状动脉粥样硬化形成相关。
作者 薛亚彬
出处 《中国医药指南》 2012年第15期542-542,共1页 Guide of China Medicine
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