中医五行音乐对恶性肿瘤化疗患者癌因性疲乏的影响

Effect of traditional Chinese medicine five elements music on cancer-related fatigue of chemotherapy patients

目的探讨中医五行音乐对恶性肿瘤化疗患者癌因性疲乏和生活质量的影响。方法将80例恶性肿瘤化疗患者随机分为试验组40例和对照组40例。试验组在常规治疗护理的基础上，于化疗开始时给予中医五行音乐干预，每次60min，每天一次，每周期14d，共3个周期，每周期与化疗周期同步；对照组在常规治疗护理的同时重点给予心理护理。治疗前后对两组分别采用美国Adorson癌症中心疼痛研究小组研制的BFI对患者进行CRF评估和欧洲癌症治疗与研究组织的生活质量问卷（EORTC—QLQ—c30）对患者的生活质量进行评价。结果试验组采用中医五行音乐干预后，癌因性疲乏轻度疲乏、中度疲乏、重度疲乏分别为：37．5％、10％、2．5％，疲乏程度与治疗前比较明显减轻，治疗前后比较有统计学意义（U=6．0623，P〈0．01）；试验组治疗后中、重度疲乏率为12．5％，对照组治疗后中、重度疲乏率为40％，比较有统计学意义（U=3．2828，P〈0．01）；治疗后试验组的总体生活质量为（43．12±6．21）分，对照组总体生活质量（52．30±7．28）分，比较有统计学意义（t=4．6830，P〈0．01）。结论应用中医五行音乐对肿瘤化疗患者进行干预，可消除癌因性疲乏或缓解疲乏程度，提高患者的生活质量。

Objective To study the effect of traditional Chinese medicine （TCM） five elements music on cancer-related fatigue CRF of chemotherapy patients. Methods 80 patients were randomly divided into the experimental group and the control group equally. The experimental group was given the TCM five elements music intervention on the basis of routine care at the start of chemotherapy for 60 min, once a day for three cycles, each cycle and chemotherapy cycle were synchronic. The control group was given routine care with emphasis on psychological care. The two groups were given the CRF assessment of Brief Fatigue Inventory developed by the pain research team of the U.S. Adorson Cancer Center before and after the treatment, and the quality of life of patients was evaluated by Quality of Life Questionnaire （ EORTC-QLQ-C30 ） by the European Cancer Treatment and Research Organization. Results CRF levels of the experimental group were markedly reduced after the intervention of TCM five elements music, among which slight fatigue accounted for 37.5% , moderate fatigue accounted for 10% and serious fatigue accounted for 2.5%. There was significant difference between the two groups （ U = 6.062 3, P 〈 O. 01 ）. The proportion of moderate and serious fatigue was 12.5% in the experimental group and 40% in the control group after treatment, and there was significant difference between the two groups （ U = 3. 282 8 ,P 〈 0.01 ）. The total score of quality of life was （ 43.12 ± 6.21 ） in the experimental group and （ 52.30 ± 7.28 ） in the control group after treatment. The difference was statistically significant （ t = 4. 683 0, P 〈 0.05 ）. Conclusions Application of TCM Five Elements music intervention on chemotherapy patients can eliminate or alleviate CRF and improve the quality of life of patients.