保定市城区学龄前儿童体质指数与瘦素和胰岛素的关系

Correlation of body mass index and leptin insulin in preschool children of Baoding city in Hebei province

目的 了解河北省保定市城区学龄前儿童体质指数的变化情况,探讨其与瘦素、胰岛素水平的关系,为儿童保健和临床工作提供理论依据.方法 选择保定市城区301名幼儿园学龄前儿童,检测其身高、体重、瘦素和胰岛素等指标并进行分析.结果 体重正常、超重和肥胖者分别占58.5 %、20.9 %和20.6 %;肥胖儿童瘦素和胰岛素水平分别为（7.9±0.5）mg/L和（5.5±1.4）mIU/L均高于正常儿童,差异有统计学意义;超重儿童瘦素和胰岛素水平与正常组比较,差异无统计学意义;3～4岁男童BMI值高于女童,差异有统计学意义;与WHO推荐的儿童生长标准指标比较,男童3岁和4岁分别增长为0.9 kg/m2和1.5 kg/m2,差异有统计学意义;女童差异无统计学意义.结论 在学龄前肥胖儿童中,BMI与血清瘦素和胰岛素呈正相关性.

Objective To investigate parameters of BMI, leptin and insulin in preschool children of Baoding city in Hebei province and discuss the relationship between them. Methods With random sampling and double-blind method, body height, body weight, leptin and insulin of 301 preschool children in Baoding city of Hebei province were exam- ined. Results The BMI levels of boys in 3-4 years old were higher than thoes of girls. The BMI levels in children of overweight and obesity were 16.92 and 17.69, higher than the levels of the normal group. Correctted with the normal group, the leptin and insulin levels of obesity were（7.9 ± 0.4） mg/L and（ 5.5 ± 1.4） mlU/L, also increased significantly. The correlated coefficients of the BMI and serum leptin and insulin levels in obesity were 0. 407and 0. 351 respectively, they were statistical significant. Conclusion In city, the BMI of preschool children in obesity correlated with serum leptin and insulin levels positively.