河北省15个县孕前优生健康检查结果分析

Pre-pregnancy physical examination： analysis of 157 885 participants in 15 counties of Hebei Province

目的 筛查出生缺陷发生风险因素,预防出生缺陷的发生、提高出生人口素质.方法 在河北省＂15个国家免费孕前优生健康检查＂项目试点县（市）经过统一培训,按照〈河北省开展免费孕前优生健康检查工作实施方案〉要求,参加免费孕前优生健康检查夫妇签署知情同意书,由专人负责检查和填写〈孕前优生健康检查技术服务手册〉,各县成立专家组进行风险评估和优生咨询指导.结果 河北省15个县（市）共有200 137例接受有关优生优育和孕前优生健康教育,157 885例接受免费孕前优生健康检查,筛查出高风险人群20 775例,占13.2 %;早孕随访率为31.5 %.结论 通过免费孕前优生健康检查工作,提升了计划生育系统的技术服务能力和水平,提高了育龄群众的优生优育意识,为探索筛查出生缺陷高风险人群、出生缺陷风险因素及降低出生缺陷发生率提供了依据.

Objective To identify risk factors for adverse pregnancy outcomes with emphases on birth defects in pre-pregnant populations. Methods Staff from family planning service stations in fifteen national pilot counties where the free pre-pregnaney physical examination was carried out were trained. Couples who planned to become pregnant were invited to participate in the free pre-pregnant examination after signing an informed consent agreement. The examination, risk assessment, and counseling were performed by trained staff. Results A total of 200 137 men and women received repro- ductive health education and counseling. Of these participants, 157 885 received free pre-pregnancy physical examination and 20 775 （ 13.2 % ） individuals were found to have one or more risk factors for adverse pregnancy outcomes. 31.5 % women who became pregnant following the examination received prenatal care in the first trimester, and those with risk factors were provided targeted care. Conclusion A large proportion of women and their partners had factors that may be associated with risks for adverse pregnancy outcomes including birth defects. Free pre-pregnancy physical examination is a good measure to identify these factors so that risks for adverse pregnancy outcomes could be eliminated or reduced through education, counseling, and health promotion.