急性出血性脑卒中T波峰-末间期变化的临床研究

stroke Clinical study of Tpeak-Tend interval in patients with acute hemorrhagic

目的观察急性出血性脑卒中患者心电图T波峰-末间期（Tp—Te间期），并探讨其对出血性脑卒中患者近期预后的预测价值。方法测量103例急性出血性脑卒中患者和100例健康人心电图V2～V4导联Tp—Te间期，并采用心率校正得出Tp—Te/,√RR。比较患者与健康组V2～V4导联Tp—Te、Tp—Te，√RR平均值的差别；根据患者住院期间死亡与否分为存活组和死亡组，比较两组V2～V4导联Tp—Te、Tp—Te／,√RR平均值。结果急性出血性脑出血患者V2-V4导联Tp—Te、TO—Te／√RR平均值较之于健康对照组均明显延长，差异有统计学意义（P〈0．01）；在急性出血性脑卒中患者中，住院期间死亡组V2-V4导联Tp—Te、Tp—Te／√RR平均值较之于存活组均明显延长，且差异有统计学意义（P〈0．05）。结论急性出血性脑卒中可使患者Tp—Te间期延长，Tp—Te间期变化与患者临床预后密切相关，对患者Tp—Te间期进行研究有助于患者临床预后的判定。

Objective To investigate the changes and the prognostic value of Tpeak-Tend interval （Tp-Te） in patients with acute hemorrhagic stroke（AHS）. Methods The standard 12-lead electrocardiogram （ECG） was taken in 103 acute hemorrhagic stroke patients and 100 healthy people. Then, Tp-Te were measured in leads V2 - V4 and corrected by heart rate （Tp-Te/√RR Differences of Tp-Te and Tp-Te/√RR were studied between patients and healthy people. According to the clinical results, the patients were divided into two groups, the survival group and the death group. Differences of Tp-Te and Tp-Te/√RR between the two groups were compared.. Results Tp-Te and Tp-Te/√RR of leads V2 - V4 in patients with acute hemorrhagic stroke were longer than healthy people, and the differences were statistically significant （P〈0.01）. Tp-Te and Tp-Te/√RR of leads V2-V4 in the death group were longer than the survival group, and the differences were statistically significant （P 〈0.05）. Conclusion The dispersion of ventricular depolarization of patients with acute hemorrhagic stroke is greater than healthy people. Tp-Te may have some value for clinical prognosis in patients with acute hemorrhagic stroke.