摘要
双炔失碳酯为一种女用口服探亲避孕药。实验证明本品在动物经阴道给药具有显著的抗生育作用。其抗着床作用优于口服给药法。经阴道给药法方便易行,且无明显不良反应。本资料可为临床研究提供借鉴。
Anordrin, which has been widely used as an oral contraceptive tablet in China, administered intra-vaginally at different levels of dose possessed marked antifertiiity effects in Sprague Dawley rats. The anti-implantation efficiency of the compound given intra-vaginally was superior to that of oral dosing in some respects. This kind of medication was feasible, convenient to use and with no serious side effects. Our investigation provides the experimental date for clinical study of using this drug vaginally.
出处
《中国药理学通报》
CAS
CSCD
北大核心
1990年第2期122-125,共4页
Chinese Pharmacological Bulletin
关键词
双快失碳酯
抗生育
Anordrin
contraceptive
Antifertility
Intra-vaginal administation
