胺碘酮片治疗老年性心律失常48例临床观察

48 examples clinical observation of Amiodarone tablets in treatment of senile arrhythmia

目的观察胺碘酮片治疗老年性心律失常的疗效。方法收集老年性心律失常患者48例,随机分组患者为观察组28例,给予胺碘酮片0.2 g/次,2次/d口服;对照组20例患者,给予心得安5mg/次,2次/d口服;疗程结束后观察两组患者的疗效。结果观察组总有效率为92.9%,对照组为80%;观察组心电图总有效率86.7%,对照组为75%;两组间在临床症状和心电图改善方面比较具有显著性差异(P<0.05)。结论胺碘酮片能有效治疗老年性心律失常。

Objective To observe the therapy of amiodarone tablets by oral medication treating senile arrhythmia. Methods We randomly divided 48 patients owned senile arrhythmia into a control group （ n = 20） and a treatment group （ n = 28 ）. Observation group given amiodarone tablets twice a day, 0. 2 g every time while the control group given propranolol twice a day, 5 mg every time. After that treatment observe the therapy of the two groups patients. Results The total effective rate of treatment group was 92. 9% , 80% in the control group. Electrocardiogram total effective rate of treatment group was 86.7 % ,75 % in the control group, there was significant difference in clinical symptoms and electrocardiogram improvement aspects between the two groups （ P 〈 0. 05 ）. Conclusion Amiodarone had significant effective in treatment of senile arrhythmia.