维库溴铵治疗硫丹中毒13例临床观察

Clinical Therapeutic Effect of Vecuronium Bromide On 13 cases of Endosulfan Poisoning

目的探讨维库溴铵治疗硫丹中毒所致剧烈抽搐的疗效。方法 13例硫丹中毒患者均出现全身频繁持续性抽搐,常规给予安定、苯巴比妥,如不能控制发作,静脉给予维库溴铵4 mg,继以1～2mg/h速度持续静脉泵注,并常规给予洗胃、综合及对症支持治疗。结果给予维库溴铵后,5例于40min内抽搐得到有效控制,其余8例于2～5 h内抽搐基本被控制;维库溴铵维持时间2 d～1周;平均机械通气时间3 d;本组无死亡病例。结论维库溴铵可有效控制硫丹中毒所致的顽固性抽搐,提高抢救成功率。

Objective Vecuronium bromide in the treatment of endosulfan poisoning caused by violent convulsions effect. Methods 13 cases of endosulfan poisoning haveoccurred in patients with persistent generalized convulsions frequently, routinely given stability, phenobarbital, if they can not control the seizures, intra- venous vecuronium 4 mg, followed by 1 ~ 2 mg/h speed continuous intravenous infusion, Gastric lavage was routinely given, synthesis, and symptomatic and supportive treatment. Results After giving vecuronium, 5 ca- ses in the effective control of seizures within 40 min, and the remaining 8 patients within the twitch in 2 - 5 h basically control ; duration of vecuronium 2 d - 1 w ; the average duration of mechanical ventilation 3 d ; There was no Deaths. Conclusion Vecuronium endosulfan poisoning can be effectively controlled due tointractable seizures and improve the success rate.